YRC Public Data Repository - Protein Structure Prediction

Protein:	MIS12
Organism:	Homo sapiens
Length:	205 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MIS12.

Description	E-value	Query Range	Subject Range
gi\|109112949, gi... - gi\|109112949\|ref\|XP_001101672.1\| PREDICTED: similar to MIS12 homolog isoform 2 [Macaca mulatta], gi\|...	9.0E-98	[1..205]	[1..205]
MIS12_RAT - Protein MIS12 homolog OS=Rattus norvegicus GN=Mis12 PE=2 SV=2	1.0E-93	[1..203]	[1..204]
MIS12_MOUSE - Protein MIS12 homolog OS=Mus musculus GN=Mis12 PE=2 SV=1	5.0E-93	[1..203]	[1..204]
MIS12_BOVIN - Protein MIS12 homolog OS=Bos taurus GN=MIS12 PE=2 SV=1	1.0E-89	[1..205]	[1..206]
gi\|73956301 - gi\|73956301\|ref\|XP_545523.2\| PREDICTED: similar to MIS12 homolog [Canis familiaris]	6.0E-79	[1..204]	[1..205]
gi\|16551356 - gi\|16551356\|dbj\|BAB71088.1\| unnamed protein product [Homo sapiens]	1.0E-75	[1..159]	[1..159]
gi\|31419547, gi\|... - gi\|41055205\|ref\|NP_956672.1\| MIS12 homolog [Danio rerio], gi\|31419547\|gb\|AAH53260.1\| Zgc:64116 [Dani...	2.0E-75	[8..203]	[16..213]
MIS12_CHICK - Protein MIS12 homolog OS=Gallus gallus GN=MIS12 PE=2 SV=1	9.0E-64	[1..203]	[1..204]

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Predicted Domain #1

Region A:
Residues: [1-205]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVDPMTYEA QFFGFTPQTC MLRIYIAFQD YLFEVMQAVE QVILKKLDGI PDCDISPVQI  60
   61 RKCTEKFLCF MKGHFDNLFS KMEQLFLQLI LRIPSNILLP EDKCKETPYS EEDFQHLQKE 120
  121 IEQLQEKYKT ELCTKQALLA ELEEQKIVQA KLKQTLTFFD ELHNVGRDHG TSDFRESLVS 180
  181 LVQNSRKLQN IRDNVEKESK RLKIS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits