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View Structure Prediction Details

Protein: PNO1
Organism: Homo sapiens
Length: 252 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PNO1.

Description E-value Query
Range		 Subject
Range
PNO1_RAT - RNA-binding protein PNO1 OS=Rattus norvegicus GN=Pno1 PE=2 SV=1
 4.0E-54 [5..252] [1..248]
PNO1_MOUSE - RNA-binding protein PNO1 OS=Mus musculus GN=Pno1 PE=1 SV=1
 1.0E-53 [5..252] [1..248]
PNO1_BOVIN - RNA-binding protein PNO1 OS=Bos taurus GN=PNO1 PE=2 SV=1
 2.0E-53 [1..252] [1..252]
gi|62897797 - gi|62897797|dbj|BAD96838.1| putatative 28 kDa protein variant [Homo sapiens]
 7.0E-53 [5..252] [1..248]
gi|109074076 - gi|109074076|ref|XP_001095777.1| PREDICTED: similar to putatative 28 kDa protein [Macaca mulatta]
 3.0E-52 [1..252] [1..252]
gi|73969846 - gi|73969846|ref|XP_531853.2| PREDICTED: similar to putatative 28 kDa protein isoform 1 [Canis famili...
 2.0E-49 [2..252] [4..254]
gi|197100798 - gi|197100798|ref|NP_001125677.1| partner of NOB1 homolog [Pongo abelii]
gi|55728843 - gi|55728843|emb|CAH91160.1| hypothetical protein [Pongo abelii]
 8.0E-47 [47..252] [1..206]
PNO1_XENTR - RNA-binding protein PNO1 OS=Xenopus tropicalis GN=pno1 PE=2 SV=1
 1.0E-44 [5..252] [1..236]

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Predicted Domain #1
Region A:
Residues: [1-61] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESEMETQSA RAEEGFTQVT RKGGRRAKKR QAEQLSAAGE GGDAGRMDTE EARPAKRPVF  60
   61 P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.154902
Match: 2cteA
Description: Solution structure of the 1st KH type I domain from human Vigilin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.08112579633678 bayes_pls_golite062009
nucleic acid binding 1.89421940623565 bayes_pls_golite062009
RNA binding 1.48894932873199 bayes_pls_golite062009
mRNA binding 0.0519339703868569 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [62-252] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLCGDGLLSG KEETRKIPVP ANRYTPLKEN WMKIFTPIVE HLGLQIRFNL KSRNVEIRTC  60
   61 KETKDVSALT KAADFVKAFI LGFQVEDALA LIRLDDLFLE SFEITDVKPL KGDHLSRAIG 120
  121 RIAGKGGKTK FTIENVTRTR IVLADVKVHI LGSFQNIKMA RTAICNLILG NPPSKVYGNI 180
  181 RAVASRSADR F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.69897
Match: 2annA
Description: No description for 2annA was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle