YRC Public Data Repository - Protein Structure Prediction

Protein:	NAGZ_SALPA
Organism:	Salmonella enterica subsp. enterica serovar Paratyphi A
Length:	341 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NAGZ_SALPA.

Description	E-value	Query Range	Subject Range
NAGZ_SHIFL - Beta-hexosaminidase OS=Shigella flexneri GN=nagZ PE=3 SV=2 gi\|226898117, gi... - gi\|237706907\|ref\|ZP_04537388.1\| beta-hexosaminidase [Escherichia sp. 3_2_53FAA], gi\|226898117\|gb\|EEH... NAGZ_ECO45 - Beta-hexosaminidase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=nagZ PE=3 SV=1 NAGZ_ECOUT - Beta-hexosaminidase OS=Escherichia coli (strain UTI89 / UPEC) GN=nagZ PE=3 SV=1 gi\|24051402, gi\|... - gi\|24112512\|ref\|NP_707022.1\| beta-hexosaminidase [Shigella flexneri 2a str. 301], gi\|24051402\|gb\|AAN...	4.0E-97	[1..341]	[1..341]
NAGZ_SHIDS - Beta-hexosaminidase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=nagZ PE=3 SV=1 gi\|209773074, gi... - gi\|209773074\|gb\|ACI84849.1\| beta-N-acetylglucosaminedase [Escherichia coli], gi\|209773068\|gb\|ACI8484...	5.0E-97	[1..341]	[1..341]
NAGZ_ECOBW - Beta-hexosaminidase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=nagZ PE=3 SV=1 gi\|4062671, gi\|8... - gi\|89107953\|ref\|AP_001733.1\| beta N-acetyl-glucosaminidase [Escherichia coli str. K-12 substr. W3110... EG13433 - beta N-acetyl-glucosaminidase / Beta-N-acetylglucosaminidase NAGZ_ECOLI - Beta-hexosaminidase (EC 3.2.1.52) (N-acetyl-beta-glucosaminidase) (Beta-N-acetylhexosaminidase) - Es... NAGZ_ECODH - Beta-hexosaminidase OS=Escherichia coli (strain K12 / DH10B) GN=nagZ PE=3 SV=1 EG13433 - beta N-acetyl-glucosaminidase / Beta-N-acetylglucosaminidase	6.0E-97	[1..341]	[1..341]
NAGZ_ECOK1 - Beta-hexosaminidase OS=Escherichia coli O1:K1 / APEC GN=nagZ PE=3 SV=1	9.0E-97	[1..341]	[1..341]
gi\|15830739, gi\|... - gi\|15830739\|ref\|NP_309512.1\| beta-hexosaminidase [Escherichia coli O157:H7 str. Sakai], gi\|13360949\|... gi\|189370378, gi... - gi\|189405393\|ref\|ZP_02815092.2\| beta-N-acetylhexosaminidase [Escherichia coli O157:H7 str. EC869], g... gi\|189365189, gi... - gi\|189404504\|ref\|ZP_02789904.2\| beta-N-acetylhexosaminidase [Escherichia coli O157:H7 str. EC4501], ... NAGZ_ECO57 - Beta-hexosaminidase OS=Escherichia coli O157:H7 GN=nagZ PE=3 SV=1 gi\|189403577, gi... - gi\|189403577\|ref\|ZP_02796339.2\| beta-N-acetylhexosaminidase [Escherichia coli O157:H7 str. EC4486], ... gi\|189402505, gi... - gi\|189402505\|ref\|ZP_02782828.2\| beta-N-acetylhexosaminidase [Escherichia coli O157:H7 str. EC4401], ... gi\|208737597, gi... - gi\|208822112\|ref\|ZP_03262431.1\| beta-N-acetylhexosaminidase [Escherichia coli O157:H7 str. EC4042], ... gi\|208815385, gi... - gi\|208815385\|ref\|ZP_03256564.1\| beta-N-acetylhexosaminidase [Escherichia coli O157:H7 str. EC4045], ... gi\|209773076, gi... - pir\|\|A85674 beta-N-acetylglucosaminedase [similarity] - Escherichia coli (strain O157:H7, substrain ... gi\|208808547, gi... - gi\|208808547\|ref\|ZP_03250884.1\| beta-N-acetylhexosaminidase [Escherichia coli O157:H7 str. EC4206], ... gi\|189406285, gi... - gi\|189406285\|ref\|ZP_02827516.2\| beta-N-acetylhexosaminidase [Escherichia coli O157:H7 str. EC508], g... gi\|15801224, gi\|... - gi\|15801224\|ref\|NP_287241.1\| beta-hexosaminidase [Escherichia coli O157:H7 EDL933], gi\|12514654\|gb\|A... gi\|189010668, gi... - gi\|189010668\|ref\|ZP_02808484.2\| beta-N-acetylhexosaminidase [Escherichia coli O157:H7 str. EC4076], ... gi\|188014595, gi... - gi\|188025143\|ref\|ZP_02776366.2\| beta-N-acetylhexosaminidase [Escherichia coli O157:H7 str. EC4113], ... gi\|187767887, gi... - gi\|187776316\|ref\|ZP_02801805.2\| beta-N-acetylhexosaminidase [Escherichia coli O157:H7 str. EC4196], ... gi\|254792490, gi... - gi\|254792490\|ref\|YP_003077327.1\| beta-N-acetylglucosaminidase [Escherichia coli O157:H7 str. TW14359... gi\|217318477, gi... - gi\|217328050\|ref\|ZP_03444132.1\| beta-N-acetylhexosaminidase [Escherichia coli O157:H7 str. TW14588],... NAGZ_ECO5E - Beta-hexosaminidase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=nagZ PE=3 SV=1	1.0E-96	[1..341]	[1..341]
NAGZ_SHISS - Beta-hexosaminidase OS=Shigella sonnei (strain Ss046) GN=nagZ PE=3 SV=1	1.0E-96	[1..341]	[1..341]
NAGZ_SHIB3 - Beta-hexosaminidase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=nagZ PE=3 SV=1 NAGZ_SHIBS - Beta-hexosaminidase OS=Shigella boydii serotype 4 (strain Sb227) GN=nagZ PE=3 SV=1	2.0E-96	[1..341]	[1..341]
gi\|30062640, gi\|... - gi\|30062640\|ref\|NP_836811.1\| beta-hexosaminidase [Shigella flexneri 2a str. 2457T], gi\|30040886\|gb\|A...	2.0E-96	[1..341]	[1..341]
NAGZ_ECOL6 - Beta-hexosaminidase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=nagZ PE=3 SV=1 NAGZ_ECOL6 - Beta-hexosaminidase OS=Escherichia coli O6 GN=nagZ PE=3 SV=1	4.0E-96	[1..341]	[1..341]
gi\|20806741, gi\|... - gi\|33286394\|gb\|AAQ01678.1\| beta-glucosidase [Thermoanaerobacter tengcongensis], gi\|20806741\|ref\|NP_6... gi\|223490105, gi... - gi\|254478116\|ref\|ZP_05091499.1\| Glycosyl hydrolase family 3 N terminal domain protein [Carboxydibrac... gi\|20806741, gi\|... - gi\|20806741\|ref\|NP_621912.1\| Beta-glucosidase-related glycosidase [Thermoanaerobacter tengcongensis ...	6.0E-96	[1..336]	[13..345]

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Predicted Domain #1

Region A:
Residues: [1-341]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPVMLNVEG CELDAEEREI LAHPLVGGLI LFTRNYHDPE QLRELVRQIR AASRNHLVVA  60
   61 VDQEGGRVQR FREGFTRLPA AQSFFALHGL EEGGRLAQEA GWLMASEMIA MDIDISFAPV 120
  121 LDVGHISAAI GERSYHADPA KALAMATRFI DGMHDAGMKT TGKHFPGHGA VTADSHKETP 180
  181 CDPRPETDIR GKDMSVFRAL ISENKLDAIM PAHVIYRAID PRPASGSPYW LKTVLRQELG 240
  241 FDGVIFSDDL SMEGAAIMGS YAERAQASLD AGCDMILVCN NRKGAVSVLD NLSPIKAERV 300
  301 TRLYHKGSFS RRELMDSARW KTASAQLNQL HERWQEEKAG H

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	84.39794
Match:	1tr9A
Description:	Structure of beta-hexosaminidase from Vibrio cholerae
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hexosaminidase activity	4.61132515966265	bayes_pls_golite062009
beta-N-acetylhexosaminidase activity	4.45262937902443	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	3.1190602686215	bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds	2.98773241907716	bayes_pls_golite062009
catalytic activity	2.22613067995402	bayes_pls_golite062009
hydrolase activity	1.107656067558	bayes_pls_golite062009
glucosidase activity	0.58717079348538	bayes_pls_golite062009
amylase activity	0.0914002140078796	bayes_pls_golite062009
alpha-amylase activity	0.0521244165288097	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: