YRC Public Data Repository - Protein Structure Prediction

Protein:	GNL2
Organism:	Homo sapiens
Length:	731 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GNL2.

Description	E-value	Query Range	Subject Range
gi\|12652715 - gi\|12652715\|gb\|AAH00107.1\| Guanine nucleotide binding protein-like 2 (nucleolar) [Homo sapiens] gi\|123982736, gi... - gi\|157928394\|gb\|ABW03493.1\| guanine nucleotide binding protein-like 2 (nucleolar) [synthetic constru...	450.0	[0..1]	[731..1]
gi\|114555591 - gi\|114555591\|ref\|XP_524667.2\| PREDICTED: guanine nucleotide binding protein-like 2 (nucleolar) isofo...	447.0	[0..1]	[731..1]
gi\|55725893 - gi\|55725893\|emb\|CAH89726.1\| hypothetical protein [Pongo abelii] gi\|236449324 - gi\|236449324\|ref\|NP_001153260.1\| guanine nucleotide binding protein-like 2 (nucleolar) [Pongo abelii...	440.0	[0..1]	[731..1]
gi\|74138651 - gi\|74138651\|dbj\|BAE27145.1\| unnamed protein product [Mus musculus]	427.0	[0..1]	[731..1]
gi\|71043774, gi\|... - gi\|71043774\|ref\|NP_001020907.1\| guanine nucleotide binding protein-like 2 (nucleolar) [Rattus norveg...	422.0	[0..1]	[731..1]
gi\|73976835 - gi\|73976835\|ref\|XP_532556.2\| PREDICTED: similar to Nucleolar GTP-binding protein 2 (Autoantigen NGP-...	410.0	[0..1]	[720..1]

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Predicted Domain #1

Region A:
Residues: [1-146]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKPKYKGRS TINPSKASTN PDRVQGAGGQ NMRDRATIRR LNMYRQKERR NSRGKIIKPL  60
   61 QYQSTVASGT VARVEPNIKW FGNTRVIKQS SLQKFQEEMD TVMKDPYKVV MKQSKLPMSL 120
  121 LHDRIRPHNL KVHILDTESF ETTFGP

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	58.036212
Match:	PF08153.3
Description:	No description for PF08153.3 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [147-533]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSQRKRPNLF ASDMQSLIEN AEMSTESYDQ GKDRDLVTED TGVRNEAQEE IYKKGQSKRI  60
   61 WGELYKVIDS SDVVVQVLDA RDPMGTRSPH IETYLKKEKP WKHLIFVLNK CDLVPTWATK 120
  121 RWVAVLSQDY PTLAFHASLT NPFGKGAFIQ LLRQFGKLHT DKKQISVGFI GYPNVGKSSV 180
  181 INTLRSKKVC NVAPIAGETK VWQYITLMRR IFLIDCPGVV YPSEDSETDI VLKGVVQVEK 240
  241 IKSPEDHIGA VLERAKPEYI SKTYKIDSWE NAEDFLEKLA FRTGKLLKGG EPDLQTVGKM 300
  301 VLNDWQRGRI PFFVKPPNAE PLVAPQLLPS SSLEVVPEAA QNNPGEEVTE TAGEGSESII 360
  361 KEETEENSHC DANTEMQQIL TRVRQNF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.522879
Match:	2hjgA
Description:	No description for 2hjgA was found.

Predicted Domain #3

Region A:
Residues: [534-591]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKINVVPQFS GDDLVPVEVS DLEEELESFS DEEEEEQEQQ RDDAEESSSE PEEENVGN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.39794
Match:	1egaA
Description:	GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [592-731]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTKAVIKALD EKIAKYQKFL DKAKAKKFSA VRISKGLSEK IFAKPEEQRK TLEEDVDDRA  60
   61 PSKKGKKRKA QREEEQEHSN KAPRALTSKE RRRAVRQQRP KKVGVRYYET HNVKNRNRNK 120
  121 KKTNDSEGQK HKRKKFRQKQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits