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View Structure Prediction Details

Protein: PRKACA
Organism: Homo sapiens
Length: 351 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRKACA.

Description E-value Query
Range		 Subject
Range
KAPCA_PIG - cAMP-dependent protein kinase catalytic subunit alpha OS=Sus scrofa GN=PRKACA PE=1 SV=4
 375.0 [0..1] [351..1]
gi|61354655 - gi|61354655|gb|AAX41034.1| protein kinase cAMP-dependent catalytic alpha [synthetic construct]
 375.0 [0..1] [351..1]
KAPCA_SHEEP - cAMP-dependent protein kinase catalytic subunit alpha OS=Ovis aries GN=PRKACA PE=1 SV=3
 374.0 [0..1] [351..1]
gi|191175 - gi|191175|gb|AAA37010.1| cAMP-dependent protein kinase alpha-catalytic subunit
KAPCA_CRIGR - cAMP-dependent protein kinase catalytic subunit alpha OS=Cricetulus griseus GN=PRKACA PE=1 SV=2
 373.0 [0..1] [351..1]
KAPCA_BOVIN - cAMP-dependent protein kinase catalytic subunit alpha OS=Bos taurus GN=PRKACA PE=1 SV=3
 372.0 [0..1] [351..1]
KAPCA_MOUSE - cAMP-dependent protein kinase catalytic subunit alpha OS=Mus musculus GN=Prkaca PE=1 SV=3
 371.0 [0..1] [351..1]
gi|120538615, gi... - gi|62665041|ref|XP_341662.2| PREDICTED: similar to cAMP-dependent protein kinase, alpha-catalytic su...
 371.0 [0..1] [351..1]
gi|28302248, gi|... - gi|28302248|gb|AAH46697.1| Kin-1-prov protein [Xenopus laevis], gi|148228553|ref|NP_001080696.1| pro...
 370.0 [0..1] [351..1]

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Predicted Domain #1
Region A:
Residues: [1-351] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNAAAAKKG SEQESVKEFL AKAKEDFLKK WESPAQNTAH LDQFERIKTL GTGSFGRVML  60
   61 VKHKETGNHY AMKILDKQKV VKLKQIEHTL NEKRILQAVN FPFLVKLEFS FKDNSNLYMV 120
  121 MEYVPGGEMF SHLRRIGRFS EPHARFYAAQ IVLTFEYLHS LDLIYRDLKP ENLLIDQQGY 180
  181 IQVTDFGFAK RVKGRTWTLC GTPEYLAPEI ILSKGYNKAV DWWALGVLIY EMAAGYPPFF 240
  241 ADQPIQIYEK IVSGKVRFPS HFSSDLKDLL RNLLQVDLTK RFGNLKNGVN DIKNHKWFAT 300
  301 TDWIAIYQRK VEAPFIPKFK GPGDTSNFDD YEEEEIRVSI NEKCGKEFSE F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 104.0
Match: 1ctpE
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle