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View Structure Prediction Details

Protein: ARFGAP3
Organism: Homo sapiens
Length: 516 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARFGAP3.

Description E-value Query
Range
Subject
Range
gi|54697042 - gi|54697042|gb|AAV38893.1| ADP-ribosylation factor GTPase activating protein 3 [synthetic construct]
0.0 [1..516] [1..516]
gi|109451020, gi... - gi|123999376|gb|ABM87252.1| ADP-ribosylation factor GTPase activating protein 3 [synthetic construct...
gi|20070255, gi|... - gi|47678295|emb|CAG30268.1| ARFGAP1 [Homo sapiens], gi|20070255|ref|NP_055385.2| ADP-ribosylation fa...
HGNC:661|MIM:612... - factor GTPase activating protein 3
0.0 [1..516] [1..516]
gi|55731318 - gi|55731318|emb|CAH92373.1| hypothetical protein [Pongo abelii]
ARFG3_PONAB - ADP-ribosylation factor GTPase-activating protein 3 OS=Pongo abelii GN=ARFGAP3 PE=2 SV=1
0.0 [1..516] [1..516]
gi|109094419, gi... - gi|109094419|ref|XP_001107868.1| PREDICTED: similar to ADP-ribosylation factor GTPase activating pro...
0.0 [1..516] [1..516]
ARFG3_MACFA - ADP-ribosylation factor GTPase-activating protein 3 OS=Macaca fascicularis GN=ARFGAP3 PE=2 SV=1
0.0 [1..516] [1..516]
gi|73968925 - gi|73968925|ref|XP_848847.1| PREDICTED: similar to ADP-ribosylation factor GTPase activating protein...
0.0 [1..516] [1..517]
gi|114686724 - gi|114686724|ref|XP_001171240.1| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes]
0.0 [1..516] [1..516]

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Predicted Domain #1
Region A:
Residues: [1-128]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDPSKQDIL TIFKRLRSVP TNKVCFDCGA KNPSWASITY GVFLCIDCSG SHRSLGVHLS  60
   61 FIRSTELDSN WSWFQLRCMQ VGGNASASSF FHQHGCSTND TNAKYNSRAA QLYREKIKSL 120
  121 ASQATRKH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.045757
Match: 2crwA
Description: Solution structure of the ArfGap domain of ADP-ribosylation factor GTPaseactivating protein 3 (ArfGap 3)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [129-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTDLWLDSCV VPPLSPPPKE EDFFASHVSP EVSDTAWASA IAEPSSLTSR PVETTLENNE  60
   61 GGQEQGPSVE GLNVPTKATL EVSSIIKKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [218-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNQAKKGLGA KKGSLGAQKL ANTCFNEIEK QAQAADKMKE QEDLAKVVSK EESIVSSLRL  60
   61 AYKDLEIQMK KDEKMNISGK KNVDSDRLGM GFGNCRSVIS HSVTSDMQTI EQESPIMAKP 120
  121 RKKYNDDSDD SYFTSSSSYF DEPVELRSSS FSSWDDSSDS YWKKETSKDT ETVLKTTGYS 180
  181 DRPTARR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [405-516]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPDYEPVENT DEAQKKFGNV KAISSDMYFG RQSQADYETR ARLERLSASS SISSADLFEE  60
   61 PRKQPAGNYS LSSVLPNAPD MAQFKQGVRS VAGKLSVFAN GVVTSIQDRY GS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle