YRC Public Data Repository - Protein Structure Prediction

Protein:	SNW1
Organism:	Homo sapiens
Length:	536 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SNW1.

Description	E-value	Query Range	Subject Range
gi\|109479738 - gi\|109479738\|ref\|XP_001059272.1\| PREDICTED: similar to Nuclear protein SkiP (Ski-interacting protein...	0.0	[1..536]	[63..598]
gi\|61367032, gi\|... - gi\|61367039\|gb\|AAX42943.1\| SKI interacting protein [synthetic construct], gi\|61367032\|gb\|AAX42942.1\|...	0.0	[1..536]	[1..536]
gi\|55730946 - gi\|55730946\|emb\|CAH92191.1\| hypothetical protein [Pongo abelii] SNW1_PONAB - SNW domain-containing protein 1 OS=Pongo abelii GN=SNW1 PE=2 SV=1	0.0	[1..536]	[1..536]
SNW1_BOVIN - SNW domain-containing protein 1 OS=Bos taurus GN=SNW1 PE=2 SV=1 gi\|73963758 - gi\|73963758\|ref\|XP_854211.1\| PREDICTED: similar to Nuclear protein SkiP (Ski-interacting protein) (S...	0.0	[1..536]	[1..536]
gi\|114654183 - gi\|114654183\|ref\|XP_001165674.1\| PREDICTED: SKI-interacting protein isoform 2 [Pan troglodytes]	0.0	[1..536]	[1..545]
gi\|48146983 - gi\|48146983\|emb\|CAG33714.1\| SNW1 [Homo sapiens]	0.0	[1..536]	[1..536]

Back

Predicted Domain #1

Region A:
Residues: [1-424]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALTSFLPAP TQLSQDQLEA EEKARSQRSR QTSLVSSRRE PPPYGYRKGW IPRLLEDFGD  60
   61 GGAFPEIHVA QYPLDMGRKK KMSNALAIQV DSEGKIKYDA IARQGQSKDK VIYSKYTDLV 120
  121 PKEVMNADDP DLQRPDEEAI KEITEKTRVA LEKSVSQKVA AAMPVRAADK LAPAQYIRYT 180
  181 PSQQGVAFNS GAKQRVIRMV EMQKDPMEPP RFKINKKIPR GPPSPPAPVM HSPSRKMTVK 240
  241 EQQEWKIPPC ISNWKNAKGY TIPLDKRLAA DGRGLQTVHI NENFAKLAEA LYIADRKARE 300
  301 AVEMRAQVER KMAQKEKEKH EEKLREMAQK ARERRAGIKT HVEKEDGEAR ERDEIRHDRR 360
  361 KERQHDRNLS RAAPDKRSKL QRNENRDISE VIALGVPNPR TSNEVQYDQR LFNQSKGMDS 420
  421 GFAG

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.01
Match:	1rh1A
Description:	crystal structure of the cytotoxic bacterial protein colicin B at 2.5 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.58108937165812	bayes_pls_golite062009
protein binding	2.33863707177656	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [425-536]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEDEIYNVYD QAWRGGKDMA QSIYRPSKNL DKDMYGDDLE ARIKTNRFVP DKEFSGSDRR  60
   61 QRGREGPVQF EEDPFGLDKF LEEAKQHGGS KRPSDSSRPK EHEHEGKKRR KE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: