| Protein: | ROCK1 |
| Organism: | Homo sapiens |
| Length: | 1354 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ROCK1.
| Description | E-value | Query Range |
Subject Range |
|
|
624.0 | [0..1] | [1353..670] |
|
|
614.0 | [0..1] | [1354..611] |
|
|
492.0 | [0..1] | [1354..1] |
|
|
488.0 | [0..1] | [1354..1] |
|
|
488.0 | [0..1] | [1354..1] |
|
|
486.0 | [0..1] | [1354..1] |
|
Region A: Residues: [1-439] |
1 11 21 31 41 51
| | | | | |
1 MSTGDSFETR FEKMDNLLRD PKSEVNSDCL LDGLDALVYD LDFPALRKNK NIDNFLSRYK 60
61 DTINKIRDLR MKAEDYEVVK VIGRGAFGEV QLVRHKSTRK VYAMKLLSKF EMIKRSDSAF 120
121 FWEERDIMAF ANSPWVVQLF YAFQDDRYLY MVMEYMPGGD LVNLMSNYDV PEKWARFYTA 180
181 EVVLALDAIH SMGFIHRDVK PDNMLLDKSG HLKLADFGTC MKMNKEGMVR CDTAVGTPDY 240
241 ISPEVLKSQG GDGYYGRECD WWSVGVFLYE MLVGDTPFYA DSLVGTYSKI MNHKNSLTFP 300
301 DDNDISKEAK NLICAFLTDR EVRLGRNGVE EIKRHLFFKN DQWAWETLRD TVAPVVPDLS 360
361 SDIDTSNFDD LEEDKGEEET FPIPKAFVGN QLPFVGFTYY SNRRYLSSAN PNDNRTSSNA 420
421 DKSLQESLQK TIYKLEEQL
|
| Detection Method: |  |
| Confidence: | 98.045757 |
| Match: | 2esmA |
| Description: | Crystal Structure of ROCK 1 bound to fasudil |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [440-836] |
1 11 21 31 41 51
| | | | | |
1 HNEMQLKDEM EQKCRTSNIK LDKIMKELDE EGNQRRNLES TVSQIEKEKM LLQHRINEYQ 60
61 RKAEQENEKR RNVENEVSTL KDQLEDLKKV SQNSQLANEK LSQLQKQLEE ANDLLRTESD 120
121 TAVRLRKSHT EMSKSISQLE SLNRELQERN RILENSKSQT DKDYYQLQAI LEAERRDRGH 180
181 DSEMIGDLQA RITSLQEEVK HLKHNLEKVE GERKEAQDML NHSEKEKNNL EIDLNYKLKS 240
241 LQQRLEQEVN EHKVTKARLT DKHQSIEEAK SVAMCEMEKK LKEEREAREK AENRVVQIEK 300
301 QCSMLDVDLK QSQQKLEHLT GNKERMEDEV KNLTLQLEQE SNKRLLLQNE LKTQAFEADN 360
361 LKGLEKQMKQ EINTLLEAKR LLEFELAQLT KQYRGNE
|
| Detection Method: | |
| Confidence: | 15.0 |
| Match: | 1i84S |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [837-978] |
1 11 21 31 41 51
| | | | | |
1 GQMRELQDQL EAEQYFSTLY KTQVKELKEE IEEKNRENLK KIQELQNEKE TLATQLDLAE 60
61 TKAESEQLAR GLLEEQYFEL TQESKKAASR NRQEITDKDH TVSRLEEANS MLTKDIEILR 120
121 RENEELTEKM KKAEEEYKLE KE
|
| Detection Method: | |
| Confidence: | 1.78 |
| Match: | 1jchA |
| Description: | Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [979-1147] |
1 11 21 31 41 51
| | | | | |
1 EEISNLKAAF EKNINTERTL KTQAVNKLAE IMNRKDFKID RKKANTQDLR KKEKENRKLQ 60
61 LELNQEREKF NQMVVKHQKE LNDMQAQLVE ECAHRNELQM QLASKESDIE QLRAKLLDLS 120
121 DSTSVASFPS ADETDGNLPE SRIEGWLSVP NRGNIKRYGW KKQYVVVSS
|
| Detection Method: | |
| Confidence: | 4.522879 |
| Match: | 2i1jA |
| Description: | No description for 2i1jA was found. |
|
Region A: Residues: [1148-1219] |
1 11 21 31 41 51
| | | | | |
1 KKILFYNDEQ DKEQSNPSMV LDIDKLFHVR PVTQGDVYRA ETEEIPKIFQ ILYANEGECR 60
61 KDVEMEPVQQ AE
|
| Detection Method: | |
| Confidence: | 1.09 |
| Match: | 2coaA |
| Description: | Solution structure of the PH domain of protein kinase C, D2 type from human |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1220-1278] |
1 11 21 31 41 51
| | | | | |
1 KTNFQNHKGH EFIPTLYHFP ANCDACAKPL WHVFKPPPAL ECRRCHVKCH RDHLDKKED
|
| Detection Method: | |
| Confidence: | 8.69897 |
| Match: | 1tbnA |
| Description: | NMR STRUCTURE OF A PROTEIN KINASE C-G PHORBOL-BINDING DOMAIN, MINIMIZED AVERAGE STRUCTURE |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1279-1354] |
1 11 21 31 41 51
| | | | | |
1 LICPCKVSYD VTSARDMLLL ACSQDEQKKW VTHLVKKIPK NPPSGFVRAS PRTLSTRSTA 60
61 NQSFRKVVKN TSGKTS
|
| Detection Method: | |
| Confidence: | 1.0 |
| Match: | 1btkA |
| Description: | Bruton's tyrosine kinase |
Matching Structure (courtesy of the PDB): |
|
