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View Structure Prediction Details

Protein: SLC33A1
Organism: Homo sapiens
Length: 549 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SLC33A1.

Description E-value Query
Range
Subject
Range
gi|114589980 - gi|114589980|ref|XP_516831.2| PREDICTED: acetyl-coenzyme A transporter [Pan troglodytes]
3.0E-70 [1..549] [1..549]
gi|7768591 - gi|7768591|dbj|BAA95446.1| acetyl-CoA transporter [Rattus norvegicus]
3.0E-70 [1..549] [1..550]
ACATN_MOUSE - Acetyl-coenzyme A transporter 1 OS=Mus musculus GN=Slc33a1 PE=1 SV=1
5.0E-69 [1..549] [1..550]
gi|111305069, gi... - gi|76642857|ref|XP_595974.2| PREDICTED: similar to acetyl-CoA transporter [Bos taurus], gi|115495151...
5.0E-68 [1..547] [1..548]
gi|73990449 - gi|73990449|ref|XP_542846.2| PREDICTED: similar to solute carrier family 33 (acetyl-CoA transporter)...
6.0E-66 [1..549] [1..551]
gi|32766677, gi|... - gi|41055797|ref|NP_957402.1| solute carrier family 33 (acetyl-CoA transporter), member 1 [Danio reri...
1.0E-61 [1..546] [3..540]
gi|147906204, gi... - gi|46249647|gb|AAH68928.1| MGC83170 protein [Xenopus laevis], gi|147906204|ref|NP_001084638.1| hypot...
3.0E-61 [1..549] [1..536]
gi|50752560 - gi|50752560|ref|XP_422831.1| PREDICTED: hypothetical protein [Gallus gallus]
3.0E-60 [1..549] [1..546]

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Predicted Domain #1
Region A:
Residues: [1-549]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPTISHKDS SRQRRPGNFS HSLDMKSGPL PPGGWDDSHL DSAGREGDRE ALLGDTGTGD  60
   61 FLKAPQSFRA ELSSILLLLF LYVLQGIPLG LAGSIPLILQ SKNVSYTDQA FFSFVFWPFS 120
  121 LKLLWAPLVD AVYVKNFGRR KSWLVPTQYI LGLFMIYLST QVDRLLGNTD DRTPDVIALT 180
  181 VAFFLFEFLA ATQDIAVDGW ALTMLSRENV GYASTCNSVG QTAGYFLGNV LFLALESADF 240
  241 CNKYLRFQPQ PRGIVTLSDF LFFWGTVFLI TTTLVALLKK ENEVSVVKEE TQGITDTYKL 300
  301 LFAIIKMPAV LTFCLLILTA KIGFSAADAV TGLKLVEEGV PKEHLALLAV PMVPLQIILP 360
  361 LIISKYTAGP QPLNTFYKAM PYRLLLGLEY ALLVWWTPKV EHQGGFPIYY YIVVLLSYAL 420
  421 HQVTVYSMYV SIMAFNAKVS DPLIGGTYMT LLNTVSNLGG NWPSTVALWL VDPLTVKECV 480
  481 GASNQNCRTP DAVELCKKLG GSCVTALDGY YVESIICVFI GFGWWFFLGP KFKKLQDEGS 540
  541 SSWKCKRNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.69897
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
binding 1.3181781780038 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 0.901989724654833 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 0.901989724654833 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle