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View Structure Prediction Details

Protein: MRPL49
Organism: Homo sapiens
Length: 166 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MRPL49.

Description E-value Query
Range
Subject
Range
gi|33086514, gi|... - gi|33086514|gb|AAP92569.1| Aa2-277 [Rattus norvegicus], gi|114145567|ref|NP_001041348.1| mitochondri...
6.0E-74 [1..166] [1..166]
gi|26340520 - gi|26340520|dbj|BAC33922.1| unnamed protein product [Mus musculus]
1.0E-73 [1..166] [1..166]
RM49_PONPY - Mitochondrial 39S ribosomal protein L49 - Pongo pygmaeus (Orangutan)
RM49_PONAB - 39S ribosomal protein L49, mitochondrial OS=Pongo abelii GN=MRPL49 PE=2 SV=1
5.0E-69 [1..166] [1..166]
gi|114638495, gi... - gi|114638497|ref|XP_001168645.1| PREDICTED: mitochondrial ribosomal protein L49 isoform 2 [Pan trogl...
1.0E-68 [1..166] [1..166]
gi|109105535, gi... - gi|109105537|ref|XP_001114460.1| PREDICTED: similar to mitochondrial ribosomal protein L49 isoform 3...
2.0E-68 [1..166] [1..166]
RM49_MACFA - 39S ribosomal protein L49, mitochondrial OS=Macaca fascicularis GN=MRPL49 PE=2 SV=1
3.0E-68 [1..166] [1..166]
gi|73983708 - gi|73983708|ref|XP_540868.2| PREDICTED: similar to mitochondrial ribosomal protein L49 [Canis famili...
2.0E-65 [1..166] [33..198]
RM49_BOVIN - 39S ribosomal protein L49, mitochondrial OS=Bos taurus GN=MRPL49 PE=1 SV=1
4.0E-62 [1..166] [1..166]

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Predicted Domain #1
Region A:
Residues: [1-68]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAATMFRATL RGWRTGVQRG CGLRLLSQTQ GPPDYPRFVE SVDEYQFVER LLPATRIPDP  60
   61 PKHEHYPT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [69-166]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSGWQPPRDP PPNLPYFVRR SRMHNIPVYK DITHGNRQMT VIRKVEGDIW ALQKDVEDFL  60
   61 SPLLGKTPVT QVNEVTGTLR IKGYFDQELK AWLLEKGF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.21
Match: 1d1rA
Description: YciH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.5202782628313 bayes_pls_golite062009
protein binding 0.449709643563469 bayes_pls_golite062009
nucleic acid binding 0.357124941848833 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle