YRC Public Data Repository - Protein Structure Prediction

Protein:	MED22
Organism:	Homo sapiens
Length:	200 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MED22.

Description	E-value	Query Range	Subject Range
gi\|109109902 - gi\|109109902\|ref\|XP_001101391.1\| PREDICTED: similar to surfeit 5 isoform b isoform 1 [Macaca mulatta...	314.0	[0..1]	[200..1]
gi\|114627378 - gi\|114627378\|ref\|XP_528453.2\| PREDICTED: surfeit 5 [Pan troglodytes]	312.0	[0..1]	[200..1]
MED22_RAT - Mediator of RNA polymerase II transcription subunit 22 OS=Rattus norvegicus GN=Med22 PE=2 SV=1	308.0	[0..1]	[200..1]
MED22_MOUSE - Mediator of RNA polymerase II transcription subunit 22 OS=Mus musculus GN=Med22 PE=1 SV=2	307.0	[0..1]	[200..1]
MED22_BOVIN - Mediator of RNA polymerase II transcription subunit 22 OS=Bos taurus GN=MED22 PE=2 SV=1	302.0	[0..1]	[200..1]
MED22_CHICK - Mediator of RNA polymerase II transcription subunit 22 OS=Gallus gallus GN=MED22 PE=3 SV=1	290.0	[0..1]	[200..1]
gi\|47212057 - gi\|47212057\|emb\|CAF90175.1\| unnamed protein product [Tetraodon nigroviridis]	264.0	[0..1]	[195..1]
MED22_TAKRU - Mediator of RNA polymerase II transcription subunit 22 OS=Takifugu rubripes GN=med22 PE=3 SV=2	259.0	[0..1]	[195..1]
MED22_XENLA - Mediator of RNA polymerase II transcription subunit 22 OS=Xenopus laevis GN=med22 PE=2 SV=1	248.0	[0..1]	[200..1]
gi\|31652218, gi\|... - gi\|5803183\|ref\|NP_006743.1\| surfeit 5 isoform a [Homo sapiens], gi\|55958178\|emb\|CAI12828.1\| surfeit ... gi\|60822577 - gi\|60822577\|gb\|AAX36614.1\| surfeit 5 [synthetic construct]	230.0	[0..1]	[140..1]

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Predicted Domain #1

Region A:
Residues: [1-141]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQQRALPQS KETLLQSYNK RLKDDIKSIM DNFTEIIKTA KIEDETQVSR ATQGEQDNYE  60
   61 MHVRAANIVR AGESLMKLVS DLKQFLILND FPSVNEAIDQ RNQQLRTLQE ECDRKLITLR 120
  121 DEISIDLYEL EEEYYSSSSS L

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	89.022276
Match:	PF06179.3
Description:	No description for PF06179.3 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.994	N/A	N/A	a.7.8	GAT domain

Predicted Domain #2

Region A:
Residues: [142-200]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CEANDLPLCE AYGRLDLDTD SADGLSAPLL ASPEPSAGPL QVAAPAHSHA GGPGPTEHA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits