| Protein: | LEP |
| Organism: | Homo sapiens |
| Length: | 167 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LEP.
| Description | E-value | Query Range |
Subject Range |
|
|
8.0E-88 | [1..167] | [1..167] |
|
|
1.0E-87 | [1..167] | [1..167] |
|
|
1.0E-87 | [1..167] | [1..167] |
|
|
1.0E-87 | [1..167] | [1..167] |
|
|
3.0E-87 | [1..167] | [1..167] |
|
|
2.0E-86 | [1..167] | [1..167] |
|
Region A: Residues: [1-167] |
1 11 21 31 41 51
| | | | | |
1 MHWGTLCGFL WLWPYLFYVQ AVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL 60
61 DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV LAFSKSCHLP 120
121 WASGLETLDS LGGVLEASGY STEVVALSRL QGSLQDMLWQ LDLSPGC
|
| Detection Method: |  |
| Confidence: | 75.0 |
| Match: | 1ax8A |
| Description: | HUMAN OBESITY PROTEIN, LEPTIN |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cytokine receptor binding | 6.47223189691244 | bayes_pls_golite062009 |
| receptor binding | 5.3304255990112 | bayes_pls_golite062009 |
| cytokine activity | 5.1883241815362 | bayes_pls_golite062009 |
| growth factor activity | 3.72884804690203 | bayes_pls_golite062009 |
| protein binding | 3.26483713001551 | bayes_pls_golite062009 |
| hormone activity | 2.52921243340076 | bayes_pls_golite062009 |
| binding | 2.48265117231403 | bayes_pls_golite062009 |
| prolactin receptor binding | 2.45721634350294 | bayes_pls_golite062009 |
| interleukin-6 receptor binding | 1.35761970306312 | bayes_pls_golite062009 |
| growth hormone activity | 0.858583061924711 | bayes_pls_golite062009 |
| interleukin-27 binding | 0.814859517857 | bayes_pls_golite062009 |
| ciliary neurotrophic factor receptor binding | 0.749565138698391 | bayes_pls_golite062009 |
| catalytic activity | 0.246169290135575 | bayes_pls_golite062009 |
| macrophage colony stimulating factor receptor binding | 0.227887473647222 | bayes_pls_golite062009 |
| interleukin-12 binding | 0.17299185486948 | bayes_pls_golite062009 |
