YRC Public Data Repository - Protein Structure Prediction

Protein:	FOLC_ARATH
Organism:	Arabidopsis thaliana
Length:	484 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FOLC_ARATH.

Description	E-value	Query Range	Subject Range
gi\|66852955, gi\|... - gi\|71001272\|ref\|XP_755317.1\| folic acid synthesis protein [Aspergillus fumigatus Af293], gi\|66852955...	477.0	[0..5]	[477..2]
FOLM_ARATH - Folate synthesis bifunctional protein, mitochondrial OS=Arabidopsis thaliana GN=MitHPPK/DHPS PE=2 SV...	476.0	[0..12]	[482..87]
gi\|115395918, gi... - gi\|115395918\|ref\|XP_001213598.1\| hypothetical protein ATEG_04420 [Aspergillus terreus NIH2624], gi\|1...	471.0	[0..10]	[477..7]
FOLM_PEA - Folate synthesis bifunctional protein, mitochondrial OS=Pisum sativum GN=MitHPPK/DHPS PE=1 SV=1	469.0	[0..2]	[483..33]
gi\|50508518, gi\|... - gi\|51963554\|ref\|XP_506473.1\| PREDICTED B1056G08.147 gene product [Oryza sativa (japonica cultivar-gr...	468.0	[0..12]	[480..58]
gi\|83774993 - gi\|83774993\|dbj\|BAE65116.1\| unnamed protein product [Aspergillus oryzae] gi\|169783574 - gi\|169783574\|ref\|XP_001826249.1\| hypothetical protein [Aspergillus oryzae RIB40]	466.0	[0..10]	[477..7]
FOL1_PNECA - Folic acid synthesis protein fol1 OS=Pneumocystis carinii GN=fol1 PE=1 SV=1	463.0	[0..14]	[478..296]
gi\|55793070 - gi\|55793070\|gb\|AAV65581.1\| folic acid synthesis protein [synthetic construct]	460.0	[0..14]	[478..296]

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Predicted Domain #1

Region A:
Residues: [1-484]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFTSLETTT FEEVVIALGS NVGNRMNNFK EALRLMKDYG ISVTRHSCLY ETEPVHVTDQ  60
   61 PRFLNAAIRG VTKLKPHELL NVLKKIEKEM GREENGLRYG PRPLDLDILF YGKHKIISDK 120
  121 LIIPHERIWE RPFVLAPLVD LLGTEDIDND KIVAYWHSLS MHSGGIFQAW ERLGGESLLG 180
  181 KDGIIQRVIP IGDHLWDFSK KTYVMGILNL TPDSFSDGGK FQSVDTAVSR VRSMISEGVD 240
  241 IIDIGAQSTR PMASRISSQE EIDRLIPVLK VVRGMAEMKG KLISVDTFNS EVALEAIRNG 300
  301 ADILNDVSGG SLDENMHKVV ADSDVPYMIM HMRGDPCTMQ NKENLEYNEI CKDVATELYE 360
  361 RVREAELSGI PAWRIMIDPG IGFSKGIDHN LDIVMELPKI REEMAKKSIG LSHAPILIGP 420
  421 SRKRFLGDIC GRPEASERDA ATVACVTAGI LKGANIIRVH NVRDNVDAAR LCDAMMTKRF 480
  481 KNVD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	107.0
Match:	2bmbA
Description:	X-ray structure of the bifunctional 6-hydroxymethyl-7,8- dihydroxypterin pyrophosphokinase dihydropteroate synthase from Sacchromyces cerevisiae
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.2	NCBI nr	03/2009
PSI-BLAST	2.2.22	FFAS	ffas03
PDB	10/2008	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits