YRC Public Data Repository - Protein Structure Prediction

Protein:	GSTO1
Organism:	Homo sapiens
Length:	241 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GSTO1.

Description	E-value	Query Range	Subject Range
gi\|31873364 - gi\|31873364\|emb\|CAD97673.1\| hypothetical protein [Homo sapiens]	6.0E-51	[1..241]	[50..290]
gi\|114632703 - gi\|114632703\|ref\|XP_508020.2\| PREDICTED: hypothetical protein [Pan troglodytes]	8.0E-51	[1..241]	[77..317]
gi\|57107281 - gi\|57107281\|ref\|XP_535007.1\| PREDICTED: similar to glutathione-S-transferase omega 1 isoform 1 [Cani...	3.0E-49	[1..241]	[1..241]
gi\|109131386 - gi\|109131386\|ref\|XP_001099994.1\| PREDICTED: similar to glutathione-S-transferase omega 1 [Macaca mul...	1.0E-47	[1..241]	[38..278]
GSTO1_PIG - Glutathione S-transferase omega-1 OS=Sus scrofa GN=GSTO1 PE=1 SV=2	3.0E-47	[1..241]	[1..241]
gi\|76654968 - gi\|76654968\|ref\|XP_870203.1\| PREDICTED: similar to glutathione S-transferase omega 2 [Bos taurus]	3.0E-47	[1..241]	[89..330]
gi\|50749765 - gi\|50749765\|ref\|XP_421747.1\| PREDICTED: similar to glutathione-S-transferase homolog isoform 2 [Gall...	3.0E-47	[1..241]	[1..239]
gi\|50540310, gi\|... - gi\|50540310\|ref\|NP_001002621.1\| hypothetical protein LOC436894 [Danio rerio], gi\|49904398\|gb\|AAH7596...	4.0E-47	[4..241]	[3..240]
gi\|34863805, gi\|... - gi\|56090550\|ref\|NP_001007603.1\| glutathione S-transferase omega 1 [Rattus norvegicus], gi\|50925894\|g...	8.0E-47	[1..241]	[1..241]

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Predicted Domain #1

Region A:
Residues: [1-241]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGESARSLG KGSAPPGPVP EGSIRIYSMR FCPFAERTRL VLKAKGIRHE VININLKNKP  60
   61 EWFFKKNPFG LVPVLENSQG QLIYESAITC EYLDEAYPGK KLLPDDPYEK ACQKMILELF 120
  121 SKVPSLVGSF IRSQNKEDYA GLKEEFRKEF TKLEEVLTNK KTTFFGGNSI SMIDYLIWPW 180
  181 FERLEAMKLN ECVDHTPKLK LWMAAMKEDP TVSALLTSEK DWQGFLELYL QNSPEACDYG 240
  241 L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.522879
Match:	1eemA
Description:	Class omega GST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
antioxidant activity	3.26520127994042	bayes_pls_golite062009
peroxidase activity	2.96616905270619	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	2.96616905270619	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
glutathione peroxidase activity	1.84498211544043	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.66635539173786	bayes_pls_golite062009
disulfide oxidoreductase activity	1.14955061683324	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
maleylacetoacetate isomerase activity	0.426921894831614	bayes_pls_golite062009
binding	0.419658151482326	bayes_pls_golite062009
oxidoreductase activity	0.314980210547407	bayes_pls_golite062009
protein binding	0.034515546627104	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: