YRC Public Data Repository - Protein Structure Prediction

Protein:	TAC1
Organism:	Homo sapiens
Length:	129 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TAC1.

Description	E-value	Query Range	Subject Range
gi\|109067409 - gi\|109067409\|ref\|XP_001089871.1\| PREDICTED: tachykinin, precursor 1 (substance K, substance P, neuro...	1.0E-64	[1..129]	[1..129]
gi\|73975838 - gi\|73975838\|ref\|XP_850435.1\| PREDICTED: similar to Protachykinin 1 precursor (PPT) isoform 3 [Canis ...	2.0E-64	[1..129]	[1..129]
gi\|62897475 - gi\|62897475\|dbj\|BAD96677.1\| tachykinin 1 isoform beta precursor variant [Homo sapiens]	3.0E-64	[1..129]	[1..129]
TKN1_RAT - Protachykinin-1 OS=Rattus norvegicus GN=Tac1 PE=2 SV=2	4.0E-64	[1..129]	[1..129]
gi\|114614668 - gi\|114614668\|ref\|XP_001171112.1\| PREDICTED: tachykinin 1 isoform 4 [Pan troglodytes]	1.0E-63	[1..129]	[1..129]
gi\|4454350 - gi\|4454350\|emb\|CAA90649.1\| beta preprotachykinin I [Tupaia belangeri]	3.0E-63	[1..129]	[1..129]
TKN1_MESAU - Protachykinin-1 OS=Mesocricetus auratus GN=TAC1 PE=2 SV=1	6.0E-63	[1..129]	[1..129]
TKN1_MOUSE - Protachykinin-1 OS=Mus musculus GN=Tac1 PE=2 SV=1	7.0E-63	[1..129]	[1..129]
TKN1_BOVIN - Protachykinin-1 OS=Bos taurus GN=TAC1 PE=1 SV=2	2.0E-62	[1..129]	[1..129]
gi\|4454091 - gi\|4454091\|emb\|CAA90647.1\| beta preprotachykinin I [Cavia porcellus]	5.0E-62	[1..129]	[1..129]

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Predicted Domain #1

Region A:
Residues: [1-129]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKILVALAVF FLVSTQLFAE EIGANDDLNY WSDWYDSDQI KEELPEPFEH LLQRIARRPK  60
   61 PQQFFGLMGK RDADSSIEKQ VALLKALYGH GQISHKRHKT DSFVGLMGKR ALNSVAYERS 120
  121 AMQNYERRR

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.398	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.368	a.100.1	6-phosphogluconate dehydrogenase C-terminal domain-like
View	Download	0.362	a.60.9	lambda integrase-like, N-terminal domain
View	Download	0.338	a.118.12	Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain
View	Download	0.330	a.4.5	"Winged helix" DNA-binding domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits