YRC Public Data Repository - Protein Structure Prediction

Protein:	PSPH
Organism:	Homo sapiens
Length:	225 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PSPH.

Description	E-value	Query Range	Subject Range
SERB_BOVIN - Phosphoserine phosphatase OS=Bos taurus GN=PSPH PE=2 SV=1	180.0	[0..1]	[225..1]
gi\|57087505, gi\|... - gi\|73957570\|ref\|XP_848288.1\| PREDICTED: similar to phosphoserine phosphatase isoform 2 [Canis famili...	179.0	[0..1]	[225..1]
gi\|54035442 - gb\|AAH83937.1\| Unknown (protein for MGC:97922) [Xenopus laevis] SERB_MOUSE - Phosphoserine phosphatase OS=Mus musculus GN=Psph PE=1 SV=1	179.0	[0..1]	[225..1]
gi\|50758156 - gi\|50758156\|ref\|XP_415786.1\| PREDICTED: similar to phosphoserine phosphatase; L-3-phosphoserine phos...	178.0	[0..1]	[225..28]
SERB_RAT - Phosphoserine phosphatase OS=Rattus norvegicus GN=Psph PE=2 SV=1	177.0	[0..1]	[225..1]
gi\|29726393, gi\|... - gi\|29726394\|pdb\|1L8O\|B Chain B, Molecular Basis For The Local Conformational Rearrangement Of Human ...	175.0	[0..1]	[225..1]
gi\|71679711, gi\|... - gi\|74315916\|ref\|NP_001028271.1\| phosphoserine phosphatase [Danio rerio], gi\|71679711\|gb\|AAI00057.1\| ...	175.0	[0..1]	[225..1]
gi\|114613509, gi... - gi\|114613527\|ref\|XP_001161062.1\| PREDICTED: similar to L-3-phosphoserine phosphatase isoform 16 [Pan...	173.0	[0..1]	[225..1]

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Predicted Domain #1

Region A:
Residues: [1-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISHSELRKL FYSADAVCFD VDSTVIREEG IDELAKICGV EDAVSEMTRR AMGGAVPFKA  60
   61 ALTERLALIQ PSREQVQRLI AEQPPHLTPG IRELVSRLQE RNVQVFLISG GFRSIVEHVA 120
  121 SKLNIPATNV FANRLKFYFN GEYAGFDETQ PTAESGGKGK VIKLLKEKFH FKKIIMIGDG 180
  181 ATDMEACPPA DAFIGFGGNV IRQQVKDNAK WYITDFVELL GELEE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.154902
Match:	1l8lA
Description:	Phosphoserine phosphatase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits