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View Structure Prediction Details

Protein: gi|2792366
Organism: Homo sapiens
Length: 873 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|2792366.

Description E-value Query
Range
Subject
Range
NOP14_MOUSE - Nucleolar protein 14 OS=Mus musculus GN=Nop14 PE=1 SV=2
0.0 [19..863] [3..850]
gi|149047414, gi... - ref|XP_214059.2| similar to 2610033H07Rik protein [Rattus norvegicus], gi|149047414|gb|EDM00084.1| s...
0.0 [42..863] [26..852]
NOP14 - NOP14 nucleolar protein homolog (yeast)
gi|55769587 - ref|NP_003694.1| gene near HD on 4p16.3 with homology to hypothetical S. pombe gene [Homo sapiens]
0.0 [17..863] [1..847]
gi|73951769 - gi|73951769|ref|XP_536223.2| PREDICTED: similar to CG5824-PA [Canis familiaris]
0.0 [40..863] [156..979]
gi|114592956 - gi|114592956|ref|XP_001151808.1| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]
0.0 [17..863] [1..847]
gi|148745028, gi... - gi|76620488|ref|XP_595158.2| PREDICTED: hypothetical protein isoform 6 [Bos taurus], gi|149642709|re...
0.0 [46..863] [29..859]

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Predicted Domain #1
Region A:
Residues: [1-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSLFGSRALG RSGARAMAKA KKVGARRKAS GAPAGARGGP AKANSNPFEV KVNRQKFQIL  60
   61 GRKTRHDVGL PGVSRARALR KRTQTLLKEY KERDKSNVFR DKRFGEYNSN MSPEEKMMKR 120
  121 FALEQQRHHE KKSIYNLNED EELTHYGQSL ADIEKHNDIV DSDSDAEDRG TLSAELTAAH 180
  181 FGGGGGLLHK KTQQEGEERE KPKSRKELIE ELIAKSKQEK RERQAQREDA LELTEKLDQD 240
  241 WKEIQTLLSH KTPKSENRDK KEKPKPDAYD MMVRELGFEM KAQPSNRMKT EAELAKEEQE 300
  301 HLRKLEAERL RRMLGKDEDE NVKKPKHMSA DDLNDGFVLD K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.39794
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [342-556]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDRRLLSYKD GKMNVEEDVQ EEQSKEASDP ESNEEEGDSS GGEDTEESDS PDSHLDLESN  60
   61 VESEEENEKP AKEQRQTPGK GLISGKERAG KATRDELPYT FAAPESYEEL RSLLLGRSME 120
  121 EQLLVVERIQ KCNHPSLAEG NKAKLEKLFG FLLEYVGDLA TDDPPDLTVI DKLVVHLYHL 180
  181 CQMFPESASD AIKFVLRDAM HEMEEMIETK GRAAL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1dg3A
Description: Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [557-675]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGLDVLIYLK ITGLLFPTSD FWHPVVTPAL VCLSQLLTKC PILSLQDVVK GLFVCCLFLE  60
   61 YVALSQRFIP ELINFLLGIL YIATPNKASQ GSTLVHPFRA LGKNSELLVV SAREDVATW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [676-873]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQSSLSLRWA SRLRAPTSTE ANHIRLSCLA VGLALLKRCV LMYGSLPSFH AIMGPLQALL  60
   61 TDHLADCSHP QELQELCQST LTEMESQKQL CRPLTCEKSK PVPLKLFTPR LVKVLEFGRK 120
  121 QGSSKEEQER KRLIHKHKRE FKGAVREIRK DNQFLARMQL SEIMERDAER KRKVKQLFNS 180
  181 LATQEGEWKA LKRKKFKK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.01
Match: 2i1jA
Description: No description for 2i1jA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle