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View Structure Prediction Details

Protein: BAMBI
Organism: Homo sapiens
Length: 260 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BAMBI.

Description E-value Query
Range		 Subject
Range
gi|60653877, gi|... - gi|60653879|gb|AAX29632.1| BMP and activin membrane-bound inhibitor-like [synthetic construct], gi|6...
 0.0 [1..260] [1..260]
gi|62897691 - gi|62897691|dbj|BAD96785.1| BMP and activin membrane-bound inhibitor variant [Homo sapiens]
 0.0 [1..260] [1..260]
gi|109088560 - gi|109088560|ref|XP_001106773.1| PREDICTED: BMP and activin membrane-bound inhibitor homolog (Xenopu...
 0.0 [1..260] [1..260]
gi|57039467 - gi|57039467|ref|XP_544209.1| PREDICTED: similar to BMP and activin membrane-bound inhibitor homolog ...
 0.0 [1..260] [1..260]
BAMBI_RAT - BMP and activin membrane-bound inhibitor homolog OS=Rattus norvegicus GN=Bambi PE=2 SV=1
 0.0 [1..260] [1..260]
BAMBI_SHEEP - BMP and activin membrane-bound inhibitor homolog OS=Ovis aries GN=BAMBI PE=2 SV=1
 0.0 [1..260] [1..260]
gi|76632321, gi|... - gi|92096613|gb|AAI14656.1| BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) [Bos ta...
 0.0 [1..260] [1..260]
BAMBI_MOUSE - BMP and activin membrane-bound inhibitor homolog OS=Mus musculus GN=Bambi PE=2 SV=1
 0.0 [1..260] [1..260]
gi|6006630 - gi|6006630|emb|CAB56858.1| BAMBI protein [Xenopus laevis]
 0.0 [1..260] [1..260]

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Predicted Domain #1
Region A:
Residues: [1-178] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRHSSYIFI WLQLELCAMA VLLTKGEIRC YCDAAHCVAT GYMCKSELSA CFSRLLDPQN  60
   61 SNSPLTHGCL DSLASTTDIC QAKQARNHSG TTIPTLECCH EDMCNYRGLH DVLSPPRGEA 120
  121 SGQGNRYQHD GSRNLITKVQ ELTSSKELWF RAAVIAVPIA GGLILVLLIM LALRMLRS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.11
Match: 1rewC
Description: Structural refinement of the complex of bone morphogenetic protein 2 and its type IA receptor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor activity 2.64910374554654 bayes_pls_golite062009
signal transducer activity 2.43282761870804 bayes_pls_golite062009
molecular transducer activity 2.43282761870804 bayes_pls_golite062009
binding 1.74649131569568 bayes_pls_golite062009
transforming growth factor beta binding 1.53779699320828 bayes_pls_golite062009
SMAD binding 1.15687191322558 bayes_pls_golite062009
protein binding 1.15266632427905 bayes_pls_golite062009
receptor binding 1.07792597575757 bayes_pls_golite062009
growth factor binding 0.896615500077067 bayes_pls_golite062009
receptor serine/threonine kinase binding 0.679269866160119 bayes_pls_golite062009
transforming growth factor beta receptor binding 0.614566148594713 bayes_pls_golite062009
transmembrane receptor protein serine/threonine kinase binding 0.614566148594713 bayes_pls_golite062009
type I transforming growth factor beta receptor binding 0.486943436794948 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [179-260] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENKRLQDQRQ QMLSRLHYSF HGHHSKKGQV AKLDLECMVP VSGHENCCLT CDKMRQADLS  60
   61 NDKILSLVHW GMYSGHGKLE FV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle