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View Structure Prediction Details

Protein: APLN
Organism: Homo sapiens
Length: 77 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APLN.

Description E-value Query
Range
Subject
Range
gi|74008940 - gi|74008940|ref|XP_854262.1| PREDICTED: similar to Apelin precursor (APJ endogenous ligand) [Canis f...
116.0 [0..1] [77..181]
gi|114690127 - gi|114690127|ref|XP_001144812.1| PREDICTED: hypothetical protein [Pan troglodytes]
96.0 [0..1] [71..83]
APEL_BOVIN - Apelin OS=Bos taurus GN=APLN PE=1 SV=1
95.0 [0..1] [77..1]
APEL_RAT - Apelin OS=Rattus norvegicus GN=Apln PE=1 SV=1
93.0 [0..1] [77..1]
APEL_MOUSE - Apelin OS=Mus musculus GN=Apln PE=3 SV=1
93.0 [0..1] [77..1]
gi|47226217 - gi|47226217|emb|CAG08364.1| unnamed protein product [Tetraodon nigroviridis]
86.0 [0..15] [77..1]

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Predicted Domain #1
Region A:
Residues: [1-77]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLRLCVQAL LLLWLSLTAV CGGSLMPLPD GNGLEDGNVR HLVQPRGSRN GPGPWQGGRR  60
   61 KFRRQRPRLS HKGPMPF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.563 d.68.3 SirA-like
View Download 0.383 a.4.1 Homeodomain-like
View Download 0.308 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.307 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.307 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.287 d.68.6 DNA-binding protein Sso10b (AlbA)
View Download 0.240 a.144.1 PABC (PABP) domain
View Download 0.222 a.144.1 PABC (PABP) domain
View Download 0.211 a.76.1 Iron-dependent represor protein, dimerization domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle