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View Structure Prediction Details

Protein: gi|6330833
Organism: Homo sapiens
Length: 832 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|6330833.

Description E-value Query
Range
Subject
Range
gi|28972684 - gi|28972684|dbj|BAC65758.1| mKIAA1246 protein [Mus musculus]
0.0 [14..832] [14..833]
gi|161760638, gi... - gi|161760638|ref|NP_001034788.1| leucine rich repeat and fibronectin type III domain containing 2 [R...
0.0 [48..832] [5..788]
LRFN2 - leucine rich repeat and fibronectin type III domain containing 2
gi|168269764 - gi|168269764|dbj|BAG10009.1| leucine-rich repeat and fibronectin type-III domain-containing protein ...
gi|55741571 - ref|NP_065788.1| leucine rich repeat and fibronectin type III domain containing 2 [Homo sapiens]
0.0 [48..832] [5..789]
LRFN2_MACFA - Leucine-rich repeat and fibronectin type-III domain-containing protein 2 OS=Macaca fascicularis GN=L...
0.0 [48..832] [5..789]
gi|73972801 - gi|73972801|ref|XP_538906.2| PREDICTED: similar to leucine rich repeat and fibronectin type III doma...
0.0 [48..832] [35..822]
gi|109071047 - gi|109071047|ref|XP_001114127.1| PREDICTED: similar to leucine rich repeat and fibronectin type III ...
0.0 [1..832] [772..1566]

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Predicted Domain #1
Region A:
Residues: [1-63]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LESVSGGEGC VAEPGSPGAP RSRPRCHPAG GRCCLAQALS DQTMETLLGG LLAFGMAFAV  60
   61 VDA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 2omxA
Description: No description for 2omxA was found.

Predicted Domain #2
Region A:
Residues: [64-149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CPKYCVCQNL SESLGTLCPS KGLLFVPPDI DRRTVELRLG GNFIIHISRQ DFANMTGLVD  60
   61 LTLSRNTISH IQPFSFLDLE SLRSLH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.39794
Match: 2id5A
Description: No description for 2id5A was found.

Predicted Domain #3
Region A:
Residues: [150-637]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDSNRLPSLG EDTLRGLVNL QHLIVNNNQL GGIADEAFED FLLTLEDLDL SYNNLHGLPW  60
   61 DSVRRMVNLH QLSLDHNLLD HIAEGTFADL QKLARLDLTS NRLQKLPPDP IFARSQASAL 120
  121 TATPFAPPLS FSFGGNPLHC NCELLWLRRL ERDDDLETCG SPGGLKGRYF WHVREEEFVC 180
  181 EPPLITQHTH KLLVLEGQAA TLKCKAIGDP SPLIHWVAPD DRLVGNSSRT AVYDNGTLDI 240
  241 FITTSQDSGA FTCIAANAAG EATAMVEVSI VQLPHLSNST SRTAPPKSRL SDITGSSKTS 300
  301 RGGGGSGGGE PPKSPPERAV LVSEVTTTSA LVKWSVSKSA PRVKMYQLQY NCSDDEVLIY 360
  361 RMIPASNKAF VVNNLVSGTG YDLCVLAMWD DTATTLTATN IVGCAQFFTK ADYPQCQSMH 420
  421 SQILGGTMIL VIGGIIVATL LVFIVILMVR YKVCNHEAPS KMAAAVSNVY SQTNGAQPPP 480
  481 PSSAPAGA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.522879
Match: 2dtgE
Description: No description for 2dtgE was found.

Predicted functions:

Term Confidence Notes
binding 0.431491932986215 bayes_pls_golite062009
protein binding 0.3642499004435 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [638-832]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPQGPPKVVV RNELLDFTAS LARASDSSSS SSLGSGEAAG LGRAPWRIPP SAPRPKPSLD  60
   61 RLMGAFASLD LKSQRKEELL DSRTPAGRGA GTSARGHHSD REPLLGPPAA RARSLLPLPL 120
  121 EGKAKRSHSF DMGDFAAAAA GGVVPGGYSP PRKVSNIWTK RSLSVNGMLL PFEESDLVGA 180
  181 RGTFGSSEWV MESTV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.0
Match: 1fnhA
Description: Fibronectin, different Fn3 modules
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.431491932986215 bayes_pls_golite062009
protein binding 0.3642499004435 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle