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View Structure Prediction Details

Protein: PRUNE
Organism: Homo sapiens
Length: 453 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRUNE.

Description E-value Query
Range
Subject
Range
PRUNE - prune homolog (Drosophila)
538.0 [0..1] [453..1]
gi|109016104 - gi|109016104|ref|XP_001103486.1| PREDICTED: similar to prune homolog [Macaca mulatta]
536.0 [0..1] [453..1]
PRUNE_MOUSE - Protein prune homolog OS=Mus musculus GN=Prune PE=1 SV=1
508.0 [0..1] [453..1]
PRUNE_RAT - Protein prune homolog OS=Rattus norvegicus GN=Prune PE=1 SV=1
507.0 [0..1] [453..1]
gi|73981563 - gi|73981563|ref|XP_540307.2| PREDICTED: similar to prune homolog [Canis familiaris]
489.0 [0..12] [453..106]
PRUNE_BOVIN - Protein prune homolog OS=Bos taurus GN=PRUNE PE=2 SV=1
476.0 [0..1] [453..1]

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Predicted Domain #1
Region A:
Residues: [1-367]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDYLQGCRA ALQESRPLHV VLGNEACDLD STVSALALAF YLAKTTEAEE VFVPVLNIKR  60
   61 SELPLRGDIV FFLQKVHIPE SILIFRDEID LHALYQAGQL TLILVDHHIL SKSDTALEEA 120
  121 VAEVLDHRPI EPKHCPPCHV SVELVGSCAT LVTERILQGA PEILDRQTAA LLHGTIILDC 180
  181 VNMDLKIGKA TPKDSKYVEK LEALFPDLPK RNDIFDSLQK AKFDVSGLTT EQMLRKDQKT 240
  241 IYRQGVKVAI SAIYMDLEAF LQRSNLLADL HAFCQAHSYD VLVAMTIFFN THNEPVRQLA 300
  301 IFCPHVALQT TICEVLERSH SPPLKLTPAS STHPNLHAYL QGNTQVSRKK LLPLLQEALS 360
  361 AYFDSMK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.045757
Match: 1wppA
Description: Structure of Streptococcus gordonii inorganic pyrophosphatase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [368-453]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPSGQPETAD VSREQVDKEL DRASNSLISG LSQDEEDPPL PPTPMNSLVD ECPLDQGLPK  60
   61 LSAEAVFEKC SQISLSQSTT ASLSKK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle