YRC Public Data Repository - Protein Structure Prediction

Protein:	RRM1
Organism:	Homo sapiens
Length:	792 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RRM1.

Description	E-value	Query Range	Subject Range
gi\|53127690, gi\|... - gi\|71895081\|ref\|NP_001026008.1\| ribonucleoside-diphosphate reductase M1 chain [Gallus gallus], gi\|53...	0.0	[1..792]	[1..790]
gi\|81673077 - gi\|81673077\|gb\|AAI09487.1\| LOC505537 protein [Bos taurus]	0.0	[1..792]	[64..854]
gi\|73988079 - gi\|73988079\|ref\|XP_534027.2\| PREDICTED: similar to Ribonucleoside-diphosphate reductase large subuni...	0.0	[1..792]	[1..792]
gi\|55250768, gi\|... - gi\|61557388\|ref\|NP_001013254.1\| ribonucleotide reductase M1 [Rattus norvegicus], gi\|55250768\|gb\|AAH8...	0.0	[1..792]	[1..792]
gi\|55250799 - gb\|AAH86021.1\| Unknown (protein for MGC:98095) [Xenopus laevis] RIR1_MOUSE - Ribonucleoside-diphosphate reductase large subunit OS=Mus musculus GN=Rrm1 PE=1 SV=2	0.0	[1..792]	[1..792]
gi\|114635715 - gi\|114635715\|ref\|XP_001160029.1\| PREDICTED: ribonucleoside-diphosphate reductase M1 chain isoform 4 ...	0.0	[1..792]	[1..792]
gi\|109107703 - gi\|109107703\|ref\|XP_001113010.1\| PREDICTED: ribonucleoside-diphosphate reductase M1 chain isoform 1 ...	0.0	[1..792]	[1..792]
gi\|62897131 - gi\|62897131\|dbj\|BAD96506.1\| ribonucleoside-diphosphate reductase M1 chain variant [Homo sapiens]	0.0	[1..792]	[1..792]

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Predicted Domain #1

Region A:
Residues: [1-792]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHVIKRDGRQ ERVMFDKITS RIQKLCYGLN MDFVDPAQIT MKVIQGLYSG VTTVELDTLA  60
   61 AETAATLTTK HPDYAILAAR IAVSNLHKET KKVFSDVMED LYNYINPHNG KHSPMVAKST 120
  121 LDIVLANKDR LNSAIIYDRD FSYNYFGFKT LERSYLLKIN GKVAERPQHM LMRVSVGIHK 180
  181 EDIDAAIETY NLLSERWFTH ASPTLFNAGT NRPQLSSCFL LSMKDDSIEG IYDTLKQCAL 240
  241 ISKSAGGIGV AVSCIRATGS YIAGTNGNSN GLVPMLRVYN NTARYVDQGG NKRPGAFAIY 300
  301 LEPWHLDIFE FLDLKKNTGK EEQRARDLFF ALWIPDLFMK RVETNQDWSL MCPNECPGLD 360
  361 EVWGEEFEKL YASYEKQGRV RKVVKAQQLW YAIIESQTET GTPYMLYKDS CNRKSNQQNL 420
  421 GTIKCSNLCT EIVEYTSKDE VAVCNLASLA LNMYVTSEHT YDFKKLAEVT KVVVRNLNKI 480
  481 IDINYYPVPE ACLSNKRHRP IGIGVQGLAD AFILMRYPFE SAEAQLLNKQ IFETIYYGAL 540
  541 EASCDLAKEQ GPYETYEGSP VSKGILQYDM WNVTPTDLWD WKVLKEKIAK YGIRNSLLIA 600
  601 PMPTASTAQI LGNNESIEPY TSNIYTRRVL SGEFQIVNPH LLKDLTERGL WHEEMKNQII 660
  661 ACNGSIQSIP EIPDDLKQLY KTVWEISQKT VLKMAAERGA FIDQSQSLNI HIAEPNYGKL 720
  721 TSMHFYGWKQ GLKTGMYYLR TRPAANPIQF TLNKEKLKDK EKVSKEEEEK ERNTAAMVCS 780
  781 LENRDECLMC GS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1zyzA
Description:	Structures of Yeast Ribonucloetide Reductase I
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits