YRC Public Data Repository - Protein Structure Prediction

Protein:	VPS28
Organism:	Homo sapiens
Length:	221 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS28.

Description	E-value	Query Range	Subject Range
gi\|149066083, gi... - gi\|27662178\|ref\|XP_216962.1\| PREDICTED: similar to vacuolar protein sorting 28 [Rattus norvegicus], ...	0.0	[1..221]	[1..221]
gi\|109087742, gi... - gi\|109087742\|ref\|XP_001092600.1\| PREDICTED: vacuolar protein sorting 28 homolog (S. cerevisiae) isof...	0.0	[1..221]	[1..221]
VPS28_MOUSE - Vacuolar protein sorting-associated protein 28 homolog OS=Mus musculus GN=Vps28 PE=1 SV=1	0.0	[1..221]	[1..221]
VPS28_BOVIN - Vacuolar protein sorting-associated protein 28 homolog OS=Bos taurus GN=VPS28 PE=2 SV=1 gi\|149757557 - gi\|149757557\|ref\|XP_001505046.1\| PREDICTED: similar to Vacuolar protein sorting 28 homolog (S. cerev...	0.0	[1..221]	[1..221]
gi\|33416656, gi\|... - gi\|33416656\|gb\|AAH56011.1\| Vps28-prov protein [Xenopus laevis], gi\|148234793\|ref\|NP_001080785.1\| vac... gi\|62858721, gi\|... - gi\|89266860\|emb\|CAJ82587.1\| vacuolar protein sorting 28 (yeast) [Xenopus tropicalis], gi\|62858721\|re...	0.0	[1..221]	[1..221]
gi\|62901850 - gi\|62901850\|gb\|AAY18876.1\| VPS28 [synthetic construct]	0.0	[2..221]	[26..245]
gi\|34784075, gi\|... - gi\|41053585\|ref\|NP_956884.1\| vacuolar protein sorting 28 [Danio rerio], gi\|34784075\|gb\|AAH56741.1\| V...	0.0	[1..221]	[1..222]
gi\|47229390 - gi\|47229390\|emb\|CAF99378.1\| unnamed protein product [Tetraodon nigroviridis]	0.0	[1..221]	[1..222]
gi\|73974777 - gi\|73974777\|ref\|XP_849245.1\| PREDICTED: similar to vacuolar protein sorting 28 isoform 1 [Canis fami...	0.0	[11..221]	[1..211]
gi\|29791869, gi\|... - gi\|34452693\|ref\|NP_898880.1\| vacuolar protein sorting 28 isoform 2 [Homo sapiens], gi\|29791869\|gb\|AA...	5.0E-98	[1..187]	[1..187]

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Predicted Domain #1

Region A:
Residues: [1-119]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFHGIPATPG IGAPGNKPEL YEEVKLYKNA REREKYDNMA ELFAVVKTMQ ALEKAYIKDC  60
   61 VSPSEYTAAC SRLLVQYKAA FRQVQGSEIS SIDEFCRKFR LDCPLAMERI KEDRPITIK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.045757
Match:	2cazB
Description:	No description for 2cazB was found.

Predicted functions:

Term	Confidence	Notes
binding	1.84486828479515	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [120-221]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDKGNLNRCI ADVVSLFITV MDKLRLEIRA MDEIQPDLRE LMETMHRMSH LPPDFEGRQT  60
   61 VSQWLQTLSG MSASDELDDS QVRQMLFDLE SAYNAFNRFL HA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.0
Match:	2j9wA
Description:	No description for 2j9wA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: