| Protein: | ARHGEF1 |
| Organism: | Homo sapiens |
| Length: | 912 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARHGEF1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..912] | [1..912] |
|
|
0.0 | [7..907] | [6..906] |
|
|
0.0 | [7..907] | [6..905] |
|
Region A: Residues: [1-246] |
1 11 21 31 41 51
| | | | | |
1 MEDFARGAAS PGPSRPGLVP VSIIGAEDED FENELETNSE EQNSQFQSLE QVKRRPAHLM 60
61 ALLQHVALQF EPGPLLCCLH ADMLGSLGPK EAKKAFLDFY HSFLEKTAVL RVPVPPNVAF 120
121 ELDRTRADLI SEDVQRRFVQ EVVQSQQVAV GRQLEDFRSK RLMGMTPWEQ ELAQLEAWVG 180
181 RDRASYEARE RHVAERLLMH LEEMQHTIST DEEKSAAVVN AIGLYMRHLG VRTKSGDKKS 240
241 GRNFFR
|
| Detection Method: |  |
| Confidence: | 81.522879 |
| Match: | 1shzC |
| Description: | Crystal Structure of the p115RhoGEF rgRGS Domain in A Complex with Galpha(13):Galpha(i1) Chimera |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [247-403] |
1 11 21 31 41 51
| | | | | |
1 KKVMGNRRSD EPAKTKKGLS SILDAARWNR GEPQVPDFRH LKAEVDAEKP GATDRKGGVG 60
61 MPSRDRNIGA PGQDTPGVSL HPLSLDSPDR EPGADAPLEL GDSSPQGPMS LESLAPPEST 120
121 DEGAETESPE PGDEGEPGRS GLELEPEEPP GWRELVP
|
| Detection Method: | |
| Confidence: | 2.5 |
| Match: | 1wckA |
| Description: | Crystal structure of the C-terminal domain of BclA, the major antigen of the exosporium of the Bacillus anthracis spore. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [404-773] |
1 11 21 31 41 51
| | | | | |
1 PDTLHSLPKS QVKRQEVISE LLVTEAAHVR MLRVLHDLFF QPMAECLFFP LEELQNIFPS 60
61 LDELIEVHSL FLDRLMKRRQ ESGYLIEEIG DVLLARFDGA EGSWFQKISS RFCSRQSFAL 120
121 EQLKAKQRKD PRFCAFVQEA ESRPRCRRLQ LKDMIPTEMQ RLTKYPLLLQ SIGQNTEEPT 180
181 EREKVELAAE CCREILHHVN QAVRDMEDLL RLKDYQRRLD LSHLRQSSDP MLSEFKNLDI 240
241 TKKKLVHEGP LTWRVTKDKA VEVHVLLLDD LLLLLQRQDE RLLLKSHSRT LTPTPDGKTM 300
301 LRPVLRLTSA MTREVATDHK AFYVLFTWDQ EAQIYELVAQ TVSERKNWCA LITETAGSLK 360
361 VPAPASRPKP
|
| Detection Method: | |
| Confidence: | 69.154902 |
| Match: | 1txdA |
| Description: | Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [774-912] |
1 11 21 31 41 51
| | | | | |
1 RPSPSSTREP LLSSSENGNG GRETSPADAR TERILSDLLP FCRPGPEGQL AATALRKVLS 60
61 LKQLLFPAEE DNGAGPPRDG DGVPGGGPLS PARTQEIQEN LLSLEETMKQ LEELEEEFCR 120
121 LRPLLSQLGG NSVPQPGCT
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
