YRC Public Data Repository - Protein Structure Prediction

Protein:	POLR3K, POLR2K
Organism:	Homo sapiens
Length:	58 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for POLR3K, POLR2K.

Description	E-value	Query Range	Subject Range
gi\|8248885 - gi\|8248885\|gb\|AAB27565.2\| metallothionein-I gene transcription activator [Mus sp.]	3.0E-23	[1..58]	[48..105]
gi\|26359970, gi\|... - gi\|86355514\|ref\|NP_001034457.1\| polymerase (RNA) II (DNA directed) polypeptide K isoform a [Mus musc...	6.0E-23	[1..58]	[42..99]
gi\|76673725 - gi\|76673725\|ref\|XP_601851.2\| PREDICTED: similar to sperm associated antigen 1 (predicted), partial [...	2.0E-21	[1..52]	[70..121]
gi\|47229350 - gi\|47229350\|emb\|CAF99338.1\| unnamed protein product [Tetraodon nigroviridis]	5.0E-18	[1..58]	[1..58]
gi\|89267208, gi\|... - gi\|89267208\|emb\|CAJ81412.1\| polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa [Xenopus tropic... gi\|51593702, gi\|... - gi\|51593702\|gb\|AAH78622.1\| Polr2kb protein [Xenopus laevis], gi\|49117015\|gb\|AAH72756.1\| Polr2ka prot...	2.0E-17	[1..58]	[1..58]
rpc10 - DNA-directed RNA polymerase I, II and III subunit Rpc10 RPAB4_SCHPO - DNA-directed RNA polymerases I, II, and III subunit RPABC4 OS=Schizosaccharomyces pombe (strain 972 ...	2.0E-15	[8..58]	[13..63]
gi\|115653155, gi... - gi\|115946461\|ref\|XP_001187419.1\| PREDICTED: similar to MGC79127 protein [Strongylocentrotus purpurat...	2.0E-15	[11..58]	[17..64]
gi\|2529427, gi\|2... - pir\|\|T52536 DNA-directed RNA polymerase (EC 2.7.7.6) small Zn-binding chain [validated] - fission ye...	9.0E-15	[8..58]	[13..63]

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Predicted Domain #1

Region A:
Residues: [1-58]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTQKDVQPP KQQPMIYICG ECHTENEIKS RDPIRCRECG YRIMYKKRTK RLVVFDAR

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.01
Match:	1i3qL
Description:	RBP12 subunit of RNA polymerase II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA-directed RNA polymerase activity	7.92192605116952	bayes_pls_golite062009
RNA polymerase activity	7.92192605116952	bayes_pls_golite062009
nucleotidyltransferase activity	5.52982482905852	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	3.69869496150981	bayes_pls_golite062009
transferase activity	3.33953718556603	bayes_pls_golite062009
binding	2.115263379644	bayes_pls_golite062009
catalytic activity	0.647299603114184	bayes_pls_golite062009
protein binding	0.501965310643031	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: