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View Structure Prediction Details

Protein: CRYBB2
Organism: Homo sapiens
Length: 205 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CRYBB2.

Description E-value Query
Range		 Subject
Range
CRBB2_CANLF - Beta-crystallin B2 OS=Canis lupus familiaris GN=CRYBB2 PE=2 SV=1
tr|M3WJG9|M3WJG9... - Crystallin beta B2 OS=Felis catus GN=CRYBB2 PE=3 SV=1
 2.0E-76 [1..205] [1..205]
CRBB2_MOUSE - Beta-crystallin B2 OS=Mus musculus GN=Crybb2 PE=1 SV=2
CRBB2_RAT - Beta-crystallin B2 OS=Rattus norvegicus GN=Crybb2 PE=1 SV=2
CRBB2_MESAU - Beta-crystallin B2 OS=Mesocricetus auratus GN=CRYBB2 PE=2 SV=2
 6.0E-76 [1..205] [1..205]
gi|109093638, gi... - gi|171543855|ref|NP_001116366.1| crystallin, beta B2 [Macaca mulatta], gi|109093638|ref|XP_001098886...
 1.0E-75 [1..205] [1..205]
CRBB2_BOVIN - Beta-crystallin B2 OS=Bos taurus GN=CRYBB2 PE=1 SV=3
 2.0E-75 [1..205] [1..205]
CRYBB2 - crystallin, beta B2
 6.0E-75 [2..205] [1..204]
gi|9739217 - gi|9739217|gb|AAF97950.1|AF286652_1 betaB1-crystallin [Rattus norvegicus]
 1.0E-73 [14..202] [49..237]
CRBB1_PIG - Beta-crystallin B1 OS=Sus scrofa GN=CRYBB1 PE=2 SV=1
 6.0E-73 [10..202] [49..241]

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Predicted Domain #1
Region A:
Residues: [1-205] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASDHQTQAG KPQSLNPKII IFEQENFQGH SHELNGPCPN LKETGVEKAG SVLVQAGPWV  60
   61 GYEQANCKGE QFVFEKGEYP RWDSWTSSRR TDSLSSLRPI KVDSQEHKII LYENPNFTGK 120
  121 KMEIIDDDVP SFHAHGYQEK VSSVRVQSGT WVGYQYPGYR GLQYLLEKGD YKDSSDFGAP 180
  181 HPQVQSVRRI RDMQWHQRGA FHPSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.39794
Match: 1ytqA
Description: Structure of Native Human Beta B2 Crystallin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural constituent of eye lens 3.95613127220698 bayes_pls_golite062009
binding 1.49962891213419 bayes_pls_golite062009
protein binding 0.439215717175215 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle