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View Structure Prediction Details

Protein: KRT6B
Organism: Homo sapiens
Length: 564 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KRT6B.

Description E-value Query
Range
Subject
Range
gi|109096771 - gi|109096771|ref|XP_001093676.1| PREDICTED: keratin, hair, basic, 4 [Macaca mulatta]
1.0E-73 [1..478] [1..478]
gi|57106717 - gi|57106717|ref|XP_543652.1| PREDICTED: similar to Keratin, type II cuticular Hb4 (Hair keratin, typ...
7.0E-73 [1..478] [1..465]
KRT84 - keratin 84
2.0E-72 [1..478] [1..478]
gi|114644580 - gi|114644580|ref|XP_522389.2| PREDICTED: keratin, hair, basic, 4 [Pan troglodytes]
1.0E-71 [1..478] [1..478]
gi|46485108, gi|... - gi|57012366|ref|NP_001008812.1| keratin 84 [Rattus norvegicus], gi|46485108|tpg|DAA02223.1| TPA_exp:...
6.0E-70 [1..478] [1..490]

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Predicted Domain #1
Region A:
Residues: [1-130]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASTSTTIRS HSSSRRGFSA NSARLPGVSR SGFSSISVSR SRGSGGLGGA CGGAGFGSRS  60
   61 LYGLGGSKRI SIGGGSCAIS GGYGSRAGGS YGFGGAGSGF GFGGGAGIGF GLGGGAGLAG 120
  121 GFGGPGFPVC 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.154902
Match: 1deqA
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [131-407]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPGGIQEVTV NQSLLTPLNL QIDPAIQRVR AEEREQIKTL NNKFASFIDK VRFLEQQNKV  60
   61 LDTKWTLLQE QGTKTVRQNL EPLFEQYINN LRRQLDNIVG ERGRLDSELR NMQDLVEDLK 120
  121 NKYEDEINKR TAAENEFVTL KKDVDAAYMN KVELQAKADT LTDEINFLRA LYDAELSQMQ 180
  181 THISDTSVVL SMDNNRNLDL DSIIAEVKAQ YEEIAQRSRA EAESWYQTKY EELQITAGRH 240
  241 GDDLRNTKQE IAEINRMIQR LRSEIDHVKK QCANLQA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.04
Match: 2i1jA
Description: No description for 2i1jA was found.

Predicted Domain #3
Region A:
Residues: [408-496]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIADAEQRGE MALKDAKNKL EGLEDALQKA KQDLARLLKE YQELMNVKLA LDVEIATYRK  60
   61 LLEGEECRLN GEGVGQVNIS VVQSTVSSG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 1gk4A
Description: Vimentin coil
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [497-564]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGGASGVGSG LGLGGGSSYS YGSGLGVGGG FSSSSGRATG GGLSSVGGGS STIKYTTTSS  60
   61 SSRKSYKH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle