YRC Public Data Repository - Protein Structure Prediction

Protein:	HCCS
Organism:	Homo sapiens
Length:	268 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HCCS.

Description	E-value	Query Range	Subject Range
gi\|62751775, gi\|... - gi\|62751775\|ref\|NP_005324.2\| holocytochrome c synthase (cytochrome c heme-lyase) [Homo sapiens], gi\|...	464.0	[0..1]	[268..1]
gi\|109129906, gi... - gi\|109129912\|ref\|XP_001094439.1\| PREDICTED: holocytochrome c synthase (cytochrome c heme-lyase) isof...	460.0	[0..1]	[268..1]
gi\|74007107 - gi\|74007107\|ref\|XP_537950.2\| PREDICTED: similar to Cytochrome c-type heme lyase (CCHL) (Holocytochro... gi\|29437340 - gi\|29437340\|gb\|AAH49998.1\| Similar to holocytochrome c synthase (cytochrome c heme-lyase) [Mus muscu...	457.0	[0..1]	[268..1]
gi\|109511686, gi... - gi\|109511686\|ref\|XP_001065465.1\| PREDICTED: similar to Cytochrome c-type heme lyase (CCHL) (Holocyto...	446.0	[0..1]	[268..1]
CCHL_MOUSE - Cytochrome c-type heme lyase OS=Mus musculus GN=Hccs PE=1 SV=2	446.0	[0..1]	[268..1]
gi\|76659811 - gi\|76659811\|ref\|XP_582675.2\| PREDICTED: similar to Cytochrome c-type heme lyase (CCHL) (Holocytochro...	421.0	[0..27]	[268..1]
CCHL_CHICK - Cytochrome c-type heme lyase OS=Gallus gallus GN=HCCS PE=2 SV=1	411.0	[0..1]	[268..1]
gi\|114687708, gi... - gi\|114687712\|ref\|XP_520928.2\| PREDICTED: similar to holocytochrome c-type synthetase isoform 4 [Pan ...	408.0	[0..1]	[268..1]

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Predicted Domain #1

Region A:
Residues: [1-138]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLSPSAPAV AVQASNASAS PPSGCPMHEG KMKGCPVNTE PSGPTCEKKT YSVPAHQERA  60
   61 YEYVECPIRG TAAENKENLD PSNLMPPPNQ TPAPDQPFAL STVREESSIP RADSEKKWVY 120
  121 PSEQMFWNAM LKKGWKWK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [139-268]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEDISQKDMY NIIRIHNQNN EQAWKEILKW EALHAAECPC GPSLIRFGGK AKEYSPRARI  60
   61 RSWMGYELPF DRHDWIINRC GTEVRYVIDY YDGGEVNKDY QFTILDVRPA LDSLSAVWDR 120
  121 MKVAWWRWTS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits