YRC Public Data Repository - Protein Structure Prediction

Protein:	AGR2
Organism:	Homo sapiens
Length:	175 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AGR2.

Description	E-value	Query Range	Subject Range
gi\|68012756 - gi\|68012756\|gb\|AAY84773.1\| AGR2 [Homo sapiens]	1.0E-26	[1..175]	[21..195]
gi\|57096374 - gi\|57096374\|ref\|XP_539450.1\| PREDICTED: similar to anterior gradient 2 homolog [Canis familiaris]	2.0E-26	[1..175]	[1..175]
gi\|149051137, gi... - gi\|27662826\|ref\|XP_216691.1\| PREDICTED: similar to anterior gradient 2 [Rattus norvegicus], gi\|15782...	2.0E-26	[1..175]	[1..175]
gi\|61370323, gi\|... - gi\|61370329\|gb\|AAX43477.1\| anterior gradient 2-like [synthetic construct], gi\|61370323\|gb\|AAX43476.1...	3.0E-26	[1..175]	[1..175]
gi\|109067268 - gi\|109067268\|ref\|XP_001105285.1\| PREDICTED: similar to anterior gradient 2 homolog [Macaca mulatta]	4.0E-26	[1..175]	[1..175]
AGR2_PONPY - Anterior gradient protein 2 homolog precursor - Pongo pygmaeus (Orangutan) AGR2_PONAB - Anterior gradient protein 2 homolog OS=Pongo abelii GN=AGR2 PE=2 SV=1	4.0E-26	[1..175]	[1..175]
AGR2_MOUSE - Anterior gradient protein 2 homolog OS=Mus musculus GN=Agr2 PE=1 SV=1	2.0E-25	[1..175]	[1..175]
gi\|94966801, gi\|... - gi\|94966801\|ref\|NP_001035590.1\| anterior gradient 2 homolog [Bos taurus], gi\|73587031\|gb\|AAI02973.1\|...	2.0E-24	[1..175]	[1..175]
gi\|95928472, gi\|... - gi\|95928472\|ref\|ZP_01311219.1\| thioredoxin [Desulfuromonas acetoxidans DSM 684], gi\|95135262\|gb\|EAT1...	3.0E-24	[53..157]	[5..108]

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Predicted Domain #1

Region A:
Residues: [1-175]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKIPVSAFL LLVALSYTLA RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE  60
   61 ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP 120
  121 DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALL LDNMKKALKL LKTEL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.0
Match:	1senA
Description:	Endoplasmic reticulum protein Rp19 O95881
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits