YRC Public Data Repository - Protein Structure Prediction

Protein:	IL17B
Organism:	Homo sapiens
Length:	180 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IL17B.

Description	E-value	Query Range	Subject Range
gi\|15795943\|emb\|... - unnamed protein product [Homo sapiens] IL17B_MOUSE - Interleukin-17B OS=Mus musculus GN=Il17b PE=2 SV=1	9.0E-63	[1..180]	[1..180]
gi\|62664510, gi\|... - gi\|62664510\|ref\|XP_341622.2\| PREDICTED: similar to Interleukin-17B precursor (IL-17B) (Cytokine-like...	1.0E-62	[1..180]	[1..180]
gi\|114602737 - gi\|114602737\|ref\|XP_001163413.1\| PREDICTED: interleukin 17B [Pan troglodytes]	9.0E-61	[1..180]	[1..180]
gi\|57085757 - gi\|57085757\|ref\|XP_546311.1\| PREDICTED: similar to Interleukin-17B precursor (IL-17B) (Cytokine-like...	1.0E-59	[1..180]	[1..180]
gi\|109079294 - gi\|109079294\|ref\|XP_001106071.1\| PREDICTED: interleukin 17B [Macaca mulatta]	2.0E-58	[1..180]	[1..180]
gi\|48146501 - gi\|48146501\|emb\|CAG33473.1\| IL17B [Homo sapiens]	2.0E-57	[1..180]	[1..180]
gi\|194668391, gi... - gi\|61841541\|ref\|XP_581208.1\| PREDICTED: similar to Interleukin-17B precursor (IL-17B) (Cytokine-like...	6.0E-55	[1..180]	[1..180]
IL17B_MESAU - Interleukin-17B (Fragment) OS=Mesocricetus auratus GN=IL17B PE=2 SV=1	5.0E-54	[1..178]	[1..178]

Back

Predicted Domain #1

Region A:
Residues: [1-180]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDWPHNLLFL LTISIFLGLG QPRSPKSKRK GQGRPGPLAP GPHQVPLDLV SRMKPYARME  60
   61 EYERNIEEMV AQLRNSSELA QRKCEVNLQL WMSNKRSLSP WGYSINHDPS RIPVDLPEAR 120
  121 CLCLGCVNPF TMQEDRSMVS VPVFSQVPVR RRLCPPPPRT GPCRQRAVME TIAVGCTCIF 180
  181

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.69897
Match:	1jpyA
Description:	Interleukin 17F, IL-17F
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.7172169551357	bayes_pls_golite062009
protein binding	1.71012476166555	bayes_pls_golite062009
receptor binding	1.57289088064508	bayes_pls_golite062009
cytokine activity	1.27920752329227	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: