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View Structure Prediction Details

Protein: BAG2
Organism: Homo sapiens
Length: 211 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BAG2.

Description E-value Query
Range
Subject
Range
gi|73973426 - gi|73973426|ref|XP_853118.1| PREDICTED: similar to BAG-family molecular chaperone regulator-2 [Canis...
1.0E-84 [1..211] [1..211]
BAG2_MOUSE - BAG family molecular chaperone regulator 2 OS=Mus musculus GN=Bag2 PE=1 SV=1
5.0E-84 [1..211] [1..210]
CCDS4961.1_1 - null
gi|109071591 - gi|109071591|ref|XP_001110620.1| PREDICTED: BCL2-associated athanogene 2 isoform 3 [Macaca mulatta]
1.0E-83 [1..211] [1..211]
gi|49065418 - gi|49065418|emb|CAG38527.1| BAG2 [Homo sapiens]
2.0E-83 [1..211] [1..211]
BAG2_BOVIN - BAG family molecular chaperone regulator 2 OS=Bos taurus PE=2 SV=1
6.0E-81 [1..211] [1..211]
gi|187024390, gi... - gi|39594473|emb|CAE72051.1| Hypothetical protein CBG19136 [Caenorhabditis briggsae], gi|187024390|em...
gi|157764338 - gi|157764338|ref|XP_001674512.1| Hypothetical protein CBG19136 [Caenorhabditis briggsae AF16]
5.0E-71 [9..187] [269..447]
unc-23 - status:Partially_confirmed UniProt:O61980 protein_id:AAC17781.1
2.0E-70 [13..187] [274..448]
gi|109485916 - gi|109485916|ref|XP_001073000.1| PREDICTED: similar to Bcl2-associated athanogene 2 [Rattus norvegic...
4.0E-70 [39..211] [30..201]

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Predicted Domain #1
Region A:
Residues: [1-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQAKINAKA NEGRFCRSSS MADRSSRLLE SLDQLELRVE ALREAATAVE QEKEILLEMI  60
   61 HSIQNSQDMR QISDGEREEL NLTANRLMGR TLTVEVSVET I

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.502 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.483 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.727 f.17.1 F1F0 ATP synthase subunit C
View Download 0.620 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.474 a.8.1 Bacterial immunoglobulin/albumin-binding domains

Predicted Domain #2
Region A:
Residues: [102-211]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNPQQQESLK HATRIIDEVV NKFLDDLGNA KSHLMSLYSA CSSEVPHGPV DQKFQSIVIG  60
   61 CALEDQKKIK RRLETLLRNI ENSDKAIKLL EHSKGAGSKT LQQNAESRFN 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 20.309804
Match: PF02179.7
Description: No description for PF02179.7 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.577 0.300 chaperone regulator activity a.25.1 Ferritin-like
View Download 0.430 0.045 chaperone regulator activity f.14.1 Voltage-gated potassium channels
View Download 0.492 0.036 chaperone regulator activity a.29.2 Bromodomain
View Download 0.470 0.035 chaperone regulator activity d.110.4 SNARE-like
View Download 0.543 N/A N/A a.25.1 Ferritin-like


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