YRC Public Data Repository - Protein Structure Prediction

Protein:	SNAP29
Organism:	Homo sapiens
Length:	258 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SNAP29.

Description	E-value	Query Range	Subject Range
SNP29_PONAB - Synaptosomal-associated protein 29 OS=Pongo abelii GN=SNAP29 PE=2 SV=1 SNP29_PONPY - Synaptosomal-associated protein 29 - Pongo pygmaeus (Orangutan)	3.0E-48	[1..258]	[1..258]
gi\|30584569, gi\|... - gi\|61370880\|gb\|AAX43568.1\| synaptosomal-associated protein 29kDa [synthetic construct], gi\|61370875\|...	3.0E-48	[1..258]	[1..258]
gi\|114685264 - gi\|114685264\|ref\|XP_514997.2\| PREDICTED: synaptosomal-associated protein 29 [Pan troglodytes]	7.0E-48	[1..258]	[1..258]
gi\|109093372 - gi\|109093372\|ref\|XP_001086227.1\| PREDICTED: similar to synaptosomal-associated protein 29 [Macaca mu...	4.0E-47	[1..258]	[1..258]
gi\|73996013 - gi\|73996013\|ref\|XP_543568.2\| PREDICTED: similar to synaptosomal-associated protein 29 [Canis familia...	4.0E-46	[1..258]	[1..258]
gi\|60649723, gi\|... - gi\|7769720\|gb\|AAF69517.1\|AF260577_1 SNAP-29 protein [Rattus norvegicus], gi\|62751974\|ref\|NP_446262.3...	1.0E-44	[1..258]	[1..257]
gi\|31543752, gi\|... - gi\|31543752\|ref\|NP_075837.2\| GS32 protein [Mus musculus], gi\|12836691\|dbj\|BAB23769.1\| unnamed protei...	2.0E-44	[1..258]	[1..260]
SNP29_BOVIN - Synaptosomal-associated protein 29 OS=Bos taurus GN=SNAP29 PE=2 SV=1	5.0E-43	[1..258]	[1..258]

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Predicted Domain #1

Region A:
Residues: [1-258]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAYPKSYNP FDDDGEDEGA RPAPWRDARD LPDGPDAPAD RQQYLRQEVL RRAEATAAST  60
   61 SRSLALMYES EKVGVASSEE LARQRGVLER TEKMVDKMDQ DLKISQKHIN SIKSVFGGLV 120
  121 NYFKSKPVET PPEQNGTLTS QPNNRLKEAI STSKEQEAKY QASHPNLRKL DDTDPVPRGA 180
  181 GSAMSTDAYP KNPHLRAYHQ KIDSNLDELS MGLGRLKDIA LGMQTEIEEQ DDILDRLTTK 240
  241 VDKLDVNIKS TERKVRQL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.154902
Match:	1dn1B
Description:	Syntaxin 1A N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
SNAP receptor activity	3.50393203740159	bayes_pls_golite062009
binding	1.97348867258406	bayes_pls_golite062009
transporter activity	1.74189664015129	bayes_pls_golite062009
protein binding	1.63976398283458	bayes_pls_golite062009
substrate-specific transporter activity	1.2360389745429	bayes_pls_golite062009
transmembrane transporter activity	1.13101548288086	bayes_pls_golite062009
phosphatidic acid binding	0.889573999146091	bayes_pls_golite062009
protein transporter activity	0.81087535212264	bayes_pls_golite062009
SNARE binding	0.71459772253941	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.398018181744571	bayes_pls_golite062009
ion transmembrane transporter activity	0.0981818568206971	bayes_pls_golite062009
phospholipid binding	0.0172309833091902	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: