YRC Public Data Repository - Protein Structure Prediction

Protein:	GUCA2A
Organism:	Homo sapiens
Length:	115 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GUCA2A.

Description	E-value	Query Range	Subject Range
gi\|162319024, gi... - gi\|162319024\|gb\|AAI56567.1\| Guanylate cyclase activator 2A (guanylin) [synthetic construct], gi\|1478... GUCA2A - guanylate cyclase activator 2A (guanylin)	199.0	[0..1]	[115..1]
gi\|114555875 - gi\|114555875\|ref\|XP_001172840.1\| PREDICTED: similar to guanylin isoform 2 [Pan troglodytes]	199.0	[0..1]	[115..1]
gi\|73976735 - gi\|73976735\|ref\|XP_539563.2\| PREDICTED: similar to guanylate cyclase activator 2A [Canis familiaris]	177.0	[0..1]	[115..454]
GUC2A_NOTAL - Guanylin OS=Notomys alexis GN=GUCA2A PE=3 SV=1	176.0	[0..1]	[115..1]
GUC2A_RAT - Guanylin OS=Rattus norvegicus GN=Guca2a PE=1 SV=1	176.0	[0..1]	[115..1]
gi\|109003241 - gi\|109003241\|ref\|XP_001085421.1\| PREDICTED: similar to guanylate cyclase activator 2A [Macaca mulatt...	176.0	[0..15]	[115..15]
GUC2A_MOUSE - Guanylin OS=Mus musculus GN=Guca2a PE=2 SV=1	173.0	[0..1]	[115..1]
gi\|1835224 - gi\|1835224\|emb\|CAA97974.1\| GCAP-I/guanylin precursor [Sus scrofa domestica] GUC2A_PIG - Guanylin OS=Sus scrofa GN=GUCA2A PE=3 SV=1	171.0	[0..1]	[115..1]
gi\|76615300 - gi\|76615300\|ref\|XP_610296.2\| PREDICTED: similar to guanylin [Bos taurus]	166.0	[0..1]	[115..1]

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Predicted Domain #1

Region A:
Residues: [1-115]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNAFLLFALC LLGAWAALAG GVTVQDGNFS FSLESVKKLK DLQEPQEPRV GKLRNFAPIP  60
   61 GEPVVPILCS NPNFPEELKP LCKEPNAQEI LQRLEEIAED PGTCEICAYA ACTGC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.09691
Match:	1o8rA
Description:	Proguanylin
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits