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View Structure Prediction Details

Protein: C1orf156
Organism: Homo sapiens
Length: 372 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for C1orf156.

Description E-value Query
Range		 Subject
Range
gi|114565293, gi... - gi|55588778|ref|XP_524959.1| PREDICTED: hypothetical protein MGC9084 isoform 3 [Pan troglodytes], gi...
 4.0E-91 [1..372] [1..372]
gi|109019452, gi... - gi|109019454|ref|XP_001096407.1| PREDICTED: similar to RIKEN cDNA 2810422O20 isoform 2 [Macaca mulat...
 4.0E-85 [1..372] [1..372]
MET18_RAT - Histidine protein methyltransferase 1 homolog OS=Rattus norvegicus GN=Mettl18 PE=2 SV=1
 3.0E-81 [1..371] [1..361]
MET18_MOUSE - Histidine protein methyltransferase 1 homolog OS=Mus musculus GN=Mettl18 PE=2 SV=2
 7.0E-81 [1..371] [1..361]
MET18_BOVIN - Histidine protein methyltransferase 1 homolog OS=Bos taurus GN=METTL18 PE=2 SV=1
 4.0E-75 [1..371] [1..372]
gi|56417704 - gi|56417704|emb|CAI19362.1| chromosome 1 open reading frame 156 [Homo sapiens]
 1.0E-46 [1..179] [1..179]
gi|56269509, gi|... - gi|56269509|gb|AAH87325.1| LOC495955 protein [Xenopus laevis], gi|148230062|ref|NP_001088691.1| hypo...
 5.0E-45 [1..370] [1..367]
RLMI_SHEON - Ribosomal RNA large subunit methyltransferase I OS=Shewanella oneidensis (strain MR-1) GN=rlmI PE=3 ...
SO1149 - conserved hypothetical protein
 6.0E-44 [23..357] [53..369]
RLMI_SHESR - Ribosomal RNA large subunit methyltransferase I OS=Shewanella sp. (strain MR-7) GN=rlmI PE=3 SV=1
 3.0E-43 [23..357] [53..369]

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Predicted Domain #1
Region A:
Residues: [1-372] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTFQFNFTIE DHLENELTPI RDGALTLDSS KELSVSESQK GEERDRKCSA EQFDLPQDHL  60
   61 WEHKSMENAA PSQDTDSPLS AASSSRNLEP HGKQPSLRAA KEHAMPKDLK KMLENKVIET 120
  121 LPGFQHVKLS VVKTILLKEN FPGENIVSKS FSSHSDLITG VYEGGLKIWE CTFDLLAYFT 180
  181 KAKVKFAGKK VLDLGCGSGL LGITAFKGGS KEIHFQDYNS MVIDEVTLPN VVANSTLEDE 240
  241 ENDVNEPDVK RCRKPKVTQL YKCRFFSGEW SEFCKLVLSS EKLFVKYDLI LTSETIYNPD 300
  301 YYSNLHQTFL RLLSKNGRVL LASKAHYFGV GGGVHLFQKF VEERDVFKTR ILKIIDEGLK 360
  361 RFIIEITFKF PG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 2as0A
Description: Crystal Structure of PH1915 (APC 5817): A Hypothetical RNA Methyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity 0.769739415230943 bayes_pls_golite062009
methyltransferase activity 0.0326231616309937 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle