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View Structure Prediction Details

Protein: GGH
Organism: Homo sapiens
Length: 318 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GGH.

Description E-value Query
Range		 Subject
Range
gi|34398189 - gi|34398189|gb|AAQ67184.1| CAD [Meghyperus sudeticus]
 4.0E-60 [14..312] [88..366]
gi|34398185 - gi|34398185|gb|AAQ67182.1| CAD [Leptopeza sp. NCSU-99071981]
 1.0E-58 [15..312] [89..362]
gi|34398167 - gi|34398167|gb|AAQ67173.1| CAD [Clinocera sp. NCSU-95051149]
 2.0E-58 [14..312] [88..366]
gi|34398203 - gi|34398203|gb|AAQ67191.1| CAD [Platypalpus sp. NCSU-99071984]
 7.0E-58 [14..312] [88..366]
gi|34398211 - gi|34398211|gb|AAQ67195.1| CAD [Wiedemannia sp. NCSU-99072188]
 1.0E-57 [14..312] [88..366]
gi|34398205 - gi|34398205|gb|AAQ67192.1| CAD [Rhamphomyia sp. NCSU-97010438]
 2.0E-57 [14..312] [88..367]
gi|34398201 - gi|34398201|gb|AAQ67190.1| CAD [Phora sp. JS299]
 2.0E-57 [14..312] [88..363]
gi|34398193 - gi|34398193|gb|AAQ67186.1| CAD [Neurigona quadrifasciata]
 3.0E-57 [14..312] [88..366]
gi|34398215 - gi|34398215|gb|AAQ67196.1| CAD [Atelestus pulicarius]
 3.0E-57 [14..312] [88..367]
gi|34398157 - gi|34398157|gb|AAQ67168.1| CAD [Acarteroptera recta]
 5.0E-57 [14..312] [88..366]

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Predicted Domain #1
Region A:
Residues: [1-318] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASPGCLLCV LGLLLCGAAS LELSRPHGDT AKKPIIGILM QKCRNKVMKN YGRYYIAASY  60
   61 VKYLESAGAR VVPVRLDLTE KDYEILFKSI NGILFPGGSV DLRRSDYAKV AKIFYNLSIQ 120
  121 SFDDGDYFPV WGTCLGFEEL SLLISGECLL TATDTVDVAM PLNFTGGQLH SRMFQNFPTE 180
  181 LLLSLAVEPL TANFHKWSLS VKNFTMNEKL KKFFNVLTTN TDGKIEFIST MEGYKYPVYG 240
  241 VQWHPEKAPY EWKNLDGISH APNAVKTAFY LAEFFVNEAR KNNHHFKSES EEEKALIYQF 300
  301 SPIYTGNISS FQQCYIFD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.221849
Match: 1l9xA
Description: gamma-glutamyl hydrolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity 1.70348758031146 bayes_pls_golite062009
catalytic activity 1.30391542469987 bayes_pls_golite062009
binding 0.245374211061945 bayes_pls_golite062009
anthranilate synthase activity 0.243205818526006 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle