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View Structure Prediction Details

Protein: gi|16507719, gi|...
Organism: Homo sapiens
Length: 1142 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|16507719, gi|....

Description E-value Query
Range
Subject
Range
gi|109461345 - gi|109461345|ref|XP_001075350.1| PREDICTED: similar to Symplekin [Rattus norvegicus]
0.0 [1..1142] [219..1366]
gi|82903955, gi|... - gi|82903955|ref|XP_910169.1| PREDICTED: similar to Symplekin [Mus musculus], gi|51762720|ref|XP_4858...
0.0 [1..1142] [220..1375]
gi|114677942 - gi|114677942|ref|XP_001166996.1| PREDICTED: symplekin isoform 7 [Pan troglodytes]
0.0 [1..1142] [146..1287]
SYMPK - symplekin
0.0 [1..1142] [133..1274]
gi|73948140 - gi|73948140|ref|XP_533638.2| PREDICTED: similar to Symplekin [Canis familiaris]
0.0 [1..1142] [133..1275]

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Predicted Domain #1
Region A:
Residues: [1-231]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQLYKVALQ WMVKSRVISE LQEACWDMVS AMAGDIILLL DSDNDGIRTH AIKFVEGLIV  60
   61 TLSPRMADSE IPRRQEHDIS LDRIPRDHPY IQYNVLWEEG KAALEQLLKF MVHPAISSIN 120
  121 LTTALGSLAN IARQRPMFMS EVIQAYETLH ANLPPTLAKS QVSSVRKNLK LHLLSVLKHP 180
  181 ASLEFQAQIT TLLVDLGTPQ AEIARNMPSS KDTRKRPRDD SDSTLKKMKL E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [232-385]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNLGEDDEDK DLEPGPSGTS KASAQISGQS DTDITAEFLQ PLLTPDNVAN LVLISMVYLP  60
   61 EAMPASFQAI YTPVESAGTE AQIKHLARLM ATQMTAAGLG PGVEQTKQCK EEPKEEKVVK 120
  121 TESVLIKRRL SAQGQAISVV GSLSSMSPLE EEAP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [386-611]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QAKRRPEPII PVTQPRLAGA GGRKKIFRLS DVLKPLTDAQ VEAMKLGAVK RILRAEKAVA  60
   61 CSGAAQVRIK ILASLVTQFN SGLKAEVLSF ILEDVRARLD LAFAWLYQEY NAYLAAGASG 120
  121 SLDKYEDCLI RLLSGLQEKP DQKDGIFTKV VLEAPLITES ALEVVRKYCE DESRTYLGMS 180
  181 TLRDLIFKRP SRQFQYLHVL LDLSSHEKDK VRSQALLFIK RMYEKE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [612-820]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLREYVEKFA LNYLQLLVHP NPPSVLFGAD KDTEVAAPWT EETVKQCLYL YLALLPQNHK  60
   61 LIHELAAVYT EAIADIKRTV LRVIEQPIRG MGMNSPELLL LVENCPKGAE TLVTRCLHSL 120
  121 TDKVPPSPEL VKRVRDLYHK RLPDVRFLIP VLNGLEKKEV IQALPKLIKL NPIVVKEVFN 180
  181 RLLGTQHGEG NSALSPLNPG ELLIALHNI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [821-914]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSVKCDMKSI IKATNLCFAE RNVYTSEVLA VVMQQLMEQS PLPMLLMRTV IQSLTMYPRL  60
   61 GGFVMNILSR LIMKQVWKYP KVWEGFIKCC QRTK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.986 a.118.9 ENTH/VHS domain

Predicted Domain #6
Region A:
Residues: [915-1142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQSFQVILQL PPQQLGAVFD KCPELREPLL AHVRSFTPHQ QAHIPNSIMT ILEASGKQEP  60
   61 EAKEAPAGPL EEDDLEPLTL APAPAPRPPQ DLIGLRLAQE KALKRQLEEE QKLKPGGVGA 120
  121 PSSSSPSPSP SARPGPPPSE EAMDFREEGP ECETPGIFIS MDDDSGLTEA ALLDSSLEGP 180
  181 LPKETAAGGL TLKEERSPQT LAPVGEDAMK TPSPAAEDAR EPEAKGNS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.39794
Match: 1y0fA
Description: No description for 1y0fA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle