YRC Public Data Repository - Protein Structure Prediction

Protein:	SEL1L
Organism:	Homo sapiens
Length:	794 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEL1L.

Description	E-value	Query Range	Subject Range
gi\|6851089, gi\|5... - gi\|6851089\|gb\|AAF29413.1\|AF052059_1 SEL1L [Homo sapiens], sp\|Q9UBV2\|SE1L_HUMAN Sel-1 homolog precurs...	0.0	[1..794]	[1..794]
SE1L1_MESAU - Protein sel-1 homolog 1 OS=Mesocricetus auratus GN=Sel1l PE=2 SV=1	0.0	[17..794]	[17..794]
gi\|60360536 - gi\|60360536\|dbj\|BAD90512.1\| mKIAA4137 protein [Mus musculus]	0.0	[17..794]	[60..832]
gi\|84375186, gi\|... - gi\|84394204\|ref\|ZP_00992934.1\| hypothetical protein V12B01_19651 [Vibrio splendidus 12B01], gi\|84375...	0.0	[63..782]	[141..837]
gi\|73964368 - gi\|73964368\|ref\|XP_537530.2\| PREDICTED: similar to sel-1 suppressor of lin-12-like [Canis familiaris...	4.0E-99	[1..769]	[1..769]
SE1L1_RAT - Protein sel-1 homolog 1 OS=Rattus norvegicus GN=Sel1l PE=2 SV=2	6.0E-96	[17..794]	[17..794]
gi\|109084486 - gi\|109084486\|ref\|XP_001105925.1\| PREDICTED: similar to sel-1 suppressor of lin-12-like [Macaca mulat...	2.0E-95	[24..769]	[24..769]
gi\|114654253 - gi\|114654253\|ref\|XP_510102.2\| PREDICTED: sel-1 suppressor of lin-12-like [Pan troglodytes]	3.0E-93	[1..794]	[1..773]

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Predicted Domain #1

Region A:
Residues: [1-216]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVRIGLTLL LCAVLLSLAS ASSDEEGSQD ESLDSKTTLT SDESVKDHTT AGRVVAGQIF  60
   61 LDSEESELES SIQEEEDSLK SQEGESVTED ISFLESPNPE NKDYEEPKKV RKPALTAIEG 120
  121 TAHGEPCHFP FLFLDKEYDE CTSDGREDGR LWCATTYDYK ADEKWGFCET EEEAAKRRQM 180
  181 QEAEMMYQTG MKILNGSNKK SQKREAYRYL QKAASM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.0
Match:	1ouvA
Description:	Helicobacter cysteine rich protein C (HcpC)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.32969330984971	bayes_pls_golite062009
protein binding	0.559882636047776	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [217-794]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NHTKALERVS YALLFGDYLP QNIQAAREMF EKLTEEGSPK GQTALGFLYA SGLGVNSSQA  60
   61 KALVYYTFGA LGGNLIAHMV LGYRYWAGIG VLQSCESALT HYRLVANHVA SDISLTGGSV 120
  121 VQRIRLPDEV ENPGMNSGML EEDLIQYYQF LAEKGDVQAQ VGLGQLHLHG GRGVEQNHQR 180
  181 AFDYFNLAAN AGNSHAMAFL GKMYSEGSDI VPQSNETALH YFKKAADMGN PVGQSGLGMA 240
  241 YLYGRGVQVN YDLALKYFQK AAEQGWVDGQ LQLGSMYYNG IGVKRDYKQA LKYFNLASQG 300
  301 GHILAFYNLA QMHASGTGVM RSCHTAVELF KNVCERGRWS ERLMTAYNSY KDGDYNAAVI 360
  361 QYLLLAEQGY EVAQSNAAFI LDQREASIVG ENETYPRALL HWNRAASQGY TVARIKLGDY 420
  421 HFYGFGTDVD YETAFIHYRL ASEQQHSAQA MFNLGYMHEK GLGIKQDIHL AKRFYDMAAE 480
  481 ASPDAQVPVF LALCKLGVVY FLQYIRETNI RDMFTQLDMD QLLGPEWDLY LMTIIALLLG 540
  541 TVIAYRQRQH QDMPAPRPPG PRPAPPQQEG PPEQQPPQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.0
Match:	2gw1A
Description:	No description for 2gw1A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: