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View Structure Prediction Details

Protein: CDC5L
Organism: Homo sapiens
Length: 802 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDC5L.

Description E-value Query
Range
Subject
Range
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
4.0E-84 [83..799] [1823..2546]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
3.0E-78 [36..800] [776..1551]
MYH4_MOUSE - Myosin-4 OS=Mus musculus GN=Myh4 PE=2 SV=1
1.0E-77 [36..800] [778..1553]
MYH4_RAT - Myosin-4 OS=Rattus norvegicus GN=Myh4 PE=1 SV=1
2.0E-77 [36..800] [778..1553]
MYH4_CANLF - Myosin-4 OS=Canis lupus familiaris GN=MYH4 PE=3 SV=1
8.0E-77 [36..799] [778..1552]
MYH1_HORSE - Myosin-1 OS=Equus caballus GN=MYH1 PE=2 SV=1
1.0E-76 [34..800] [775..1552]

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Predicted Domain #1
Region A:
Residues: [1-77]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRIMIKGGV WRNTEDEILK AAVMKYGKNQ WSRIASLLHR KSAKQCKARW YEWLDPSIKK  60
   61 TEWSREEEEK LLHLAKL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.0
Match: 2dimA
Description: No description for 2dimA was found.

Predicted Domain #2
Region A:
Residues: [78-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTQWRTIAP IIGRTAAQCL EHYEFLLDKA AQRDNEEETT DDPRKLKPGE IDPNPETKPA  60
   61 RPDPIDMDED ELEMLSEARA RLANTQGKKA KRKAREKQLE EARRLAALQK RRELRAAGIE 120
  121 IQKKRKRKRG VDYNAEIPFE KKPALGFYDT SEENYQALDA DFRKLRQQDL DGELRSEKEG 180
  181 RDRKKDKQHL KRKKESDLPS AILQTSGVSE FTKKRSKLVL PAPQISDAEL QEVVKVGQAS 240
  241 EIARQTAEES GITNSASSTL LSEYNVTNNS VALRTPRTPA SQDRILQEAQ NLMALTNVDT 300
  301 PLKGGLNTPL HESDFSGVTP QRQVVQTPNT VLSTPFRTPS NGAEGLTP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.09691
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [426-719]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSGTTPKPVI NSTPGRTPLR DKLNINPEDG MADYSDPSYV KQMERESREH LRLGLLGLPA  60
   61 PKNDFEIVLP ENAEKELEER EIDDTYIEDA ADVDARKQAI RDAERVKEMK RMHKAVQKDL 120
  121 PRPSEVNETI LRPLNVEPPL TDLQKSEELI KKEMITMLHY DLLHHPYEPS GNKKGKTVGF 180
  181 GTNNSEHITY LEHNPYEKFS KEELKKAQDV LVQEMEVVKQ GMSHGELSSE AYNQVWEECY 240
  241 SQVLYLPGQS RYTRANLASK KDRIESLEKR LEINRGHMTT EAKRAAKMEK KMKI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.221849
Match: 2tmaA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [720-802]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLGGYQSRAM GLMKQLNDLW DQIEQAHLEL RTFEELKKHE DSAIPRRLEC LKEDVQRQQE  60
   61 REKELQHRYA DLLLEKETLK SKF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.30103
Match: 2iw5A
Description: No description for 2iw5A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle