YRC Public Data Repository - Protein Structure Prediction

Protein:	TPRKB
Organism:	Homo sapiens
Length:	175 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPRKB.

Description	E-value	Query Range	Subject Range
gi\|76628982 - gi\|76628982\|ref\|XP_597438.2\| PREDICTED: similar to PRPK (p53-related protein kinase)-binding protein...	1.0E-64	[1..175]	[168..342]
TPRKB_MOUSE - EKC/KEOPS complex subunit Tprkb OS=Mus musculus GN=Tprkb PE=1 SV=1	2.0E-61	[1..175]	[1..175]
gi\|149036592, gi... - gi\|62422579\|ref\|NP_001013948.2\| Prpk (p53-related protein kinase)-binding protein [Rattus norvegicus...	4.0E-61	[1..175]	[1..175]
gi\|12001980 - gi\|12001980\|gb\|AAG43133.1\|AF060921_1 My019 protein [Homo sapiens]	1.0E-60	[1..175]	[1..175]
gi\|109103387 - gi\|109103387\|ref\|XP_001105548.1\| PREDICTED: similar to PRPK (p53-related protein kinase)-binding pro...	4.0E-60	[1..175]	[1..175]
gi\|148229425, gi... - gi\|28175286\|gb\|AAH45235.1\| MGC53277 protein [Xenopus laevis], gi\|148229425\|ref\|NP_001079622.1\| hypot...	7.0E-60	[1..175]	[1..175]
gi\|57098381 - gi\|57098381\|ref\|XP_533004.1\| PREDICTED: similar to PRPK (p53-related protein kinase)-binding protein...	2.0E-59	[1..175]	[1..175]
gi\|39794363, gi\|... - gi\|45361497\|ref\|NP_989325.1\| hypothetical protein MGC75657 [Xenopus (Silurana) tropicalis], gi\|39794...	1.0E-56	[1..175]	[1..173]

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Predicted Domain #1

Region A:
Residues: [1-175]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLTHQLDLF PECRVTLLLF KDVKNAGDLR RKAMEGTIDG SLINPTVIVD PFQILVAANK  60
   61 AVHLYKLGKM KTRTLSTEII FNLSPNNNIS EALKKFGISA NDTSILIVYI EEGEKQINQE 120
  121 YLISQVEGHQ VSLKNLPEIM NITEVKKIYK LSSQEESIGT LLDAIICRMS TKDVL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.0
Match:	1zd0A
Description:	Crystal structure of Pfu-542154 conserved hypothetical protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits