YRC Public Data Repository - Protein Structure Prediction

Protein:	BMX
Organism:	Homo sapiens
Length:	675 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BMX.

Description	E-value	Query Range	Subject Range
gi\|33303803 - gi\|33303803\|gb\|AAQ02415.1\| BMX non-receptor tyrosine kinase [synthetic construct]	501.0	[0..1]	[675..1]
gi\|109129995 - gi\|109129995\|ref\|XP_001101349.1\| PREDICTED: BMX non-receptor tyrosine kinase isoform 3 [Macaca mulat...	496.0	[0..1]	[674..5]
gi\|3002963 - gi\|3002963\|gb\|AAC08966.1\| Etk/Bmx cytosolic tyrosine kinase [Homo sapiens]	496.0	[0..1]	[675..24]
gi\|74007139 - gi\|74007139\|ref\|XP_548870.2\| PREDICTED: similar to Cytoplasmic tyrosine-protein kinase BMX (Bone mar...	494.0	[0..1]	[674..222]
gi\|76668168 - gi\|76668168\|ref\|XP_610012.2\| PREDICTED: similar to Cytoplasmic tyrosine-protein kinase BMX (Bone mar...	480.0	[0..1]	[674..1]
gi\|15020806 - gi\|15020806\|emb\|CAC44628.1\| tyrosine protein kinase BTK [Takifugu rubripes]	459.0	[0..3]	[671..2]
BMX_MOUSE - Cytoplasmic tyrosine-protein kinase BMX OS=Mus musculus GN=Bmx PE=2 SV=1	453.0	[0..1]	[674..1]
gi\|149035848, gi... - gi\|157824055\|ref\|NP_001102486.1\| BMX non-receptor tyrosine kinase [Rattus norvegicus], gi\|149035848\|...	452.0	[0..1]	[674..5]

Back

Predicted Domain #1

Region A:
Residues: [1-139]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTKSILEEL LLKRSQQKKK MSPNNYKERL FVLTKTNLSY YEYDKMKRGS RKGSIEIKKI  60
   61 RCVEKVNLEE QTPVERQYPF QIVYKDGLLY VYASNEESRS QWLKALQKEI RGNPHLLVKY 120
  121 HSGFFVDGKF LCCQQSCKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.69897
Match:	1bwnA
Description:	Bruton's tyrosine kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [140-675]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APGCTLWEAY ANLHTAVNEE KHRVPTFPDR VLKIPRAVPV LKMDAPSSST TLAQYDNESK  60
   61 KNYGSQPPSS STSLAQYDSN SKKIYGSQPN FNMQYIPRED FPDWWQVRKL KSSSSSEDVA 120
  121 SSNQKERNVN HTTSKISWEF PESSSSEEEE NLDDYDWFAG NISRSQSEQL LRQKGKEGAF 180
  181 MVRNSSQVGM YTVSLFSKAV NDKKGTVKHY HVHTNAENKL YLAENYCFDS IPKLIHYHQH 240
  241 NSAGMITRLR HPVSTKANKV PDSVSLGNGI WELKREEITL LKELGSGQFG VVQLGKWKGQ 300
  301 YDVAVKMIKE GSMSEDEFFQ EAQTMMKLSH PKLVKFYGVC SKEYPIYIVT EYISNGCLLN 360
  361 YLRSHGKGLE PSQLLEMCYD VCEGMAFLES HQFIHRDLAA RNCLVDRDLC VKVSDFGMTR 420
  421 YVLDDQYVSS VGTKFPVKWS APEVFHYFKY SSKSDVWAFG ILMWEVFSLG KQPYDLYDNS 480
  481 QVVLKVSQGH RLYRPHLASD TIYQIMYSCW HELPEKRPTF QQLLSSIEPL REKDKH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	111.0
Match:	2h8hA
Description:	No description for 2h8hA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits