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View Structure Prediction Details

Protein: NCKAP1
Organism: Homo sapiens
Length: 1128 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NCKAP1.

Description E-value Query
Range
Subject
Range
gi|109470163 - gi|109470163|ref|XP_001067975.1| PREDICTED: similar to Nck-associated protein 1 (NAP 1) (p125Nap1) (...
1986.0 [0..1] [1128..218]
gi|114582221 - gi|114582221|ref|XP_001148485.1| PREDICTED: NCK-associated protein 1 [Pan troglodytes]
1982.0 [0..1] [1128..255]
gi|109100376 - gi|109100376|ref|XP_001099879.1| PREDICTED: similar to NCK-associated protein 1 isoform 2 [Macaca mu...
1973.0 [0..1] [1128..195]
NCKP1_MOUSE - Nck-associated protein 1 OS=Mus musculus GN=Nckap1 PE=1 SV=2
gi|151555179 - gi|151555179|gb|AAI48378.1| NCK-associated protein 1 [synthetic construct]
1948.0 [0..1] [1128..1]
gi|40788295 - gi|40788295|dbj|BAA25513.2| KIAA0587 protein [Homo sapiens]
1947.0 [0..1] [1128..38]
gi|61370741, gi|... - gi|61370741|gb|AAX43545.1| NCK-associated protein 1 [synthetic construct], gi|30583923|gb|AAP36210.1...
1946.0 [0..1] [1128..1]
NCKP1_XENLA - Nck-associated protein 1 OS=Xenopus laevis GN=nckap1 PE=2 SV=1
1916.0 [0..1] [1128..1]
gi|74004943 - gi|74004943|ref|XP_535990.2| PREDICTED: similar to NCK-associated protein 1 isoform 2 [Canis familia...
1882.0 [0..36] [1128..35]

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Predicted Domain #1
Region A:
Residues: [1-244]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRSVLQPSQ QKLAEKLTIL NDRGVGMLTR LYNIKKACGD PKAKPSYLID KNLESAVKFI  60
   61 VRKFPAVETR NNNQQLAQLQ KEKSEILKNL ALYYFTFVDV MEFKDHVCEL LNTIDVCQVF 120
  121 FDITVNFDLT KNYLDLIITY TTLMILLSRI EERKAIIGLY NYAHEMTHGA SDREYPRLGQ 180
  181 MIVDYENPLK KMMEEFVPHS KSLSDALISL QMVYPRRNLS ADQWRNAQLL SLISAPSTML 240
  241 NPAQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [245-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDTMPCEYLS LDAMEKWIIF GFILCHGILN TDATALNLWK LALQSSSCLS LFRDEVFHIH  60
   61 KAAEDLFVNI RGYNKRINDI RECKEAAVSH AGSMHRERRK FLRSALKELA TVLSDQPGLL 120
  121 GPKALFVFMA LSFARDEIIW LLRHADNMP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.590 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.452 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.411 a.25.1 Ferritin-like
View Download 0.401 c.36.1 Thiamin diphosphate-binding fold (THDP-binding)
View Download 0.393 d.210.1 Argininosuccinate synthetase, C-terminal domain
View Download 0.392 a.47.2 t-snare proteins
View Download 0.377 a.26.1 4-helical cytokines
View Download 0.373 a.26.1 4-helical cytokines
View Download 0.360 a.75.1 Ribosomal protein S7
View Download 0.348 a.63.1 Apolipophorin-III
View Download 0.296 a.1.1 Globin-like
View Download 0.254 a.126.1 Serum albumin-like
View Download 0.245 c.36.1 Thiamin diphosphate-binding fold (THDP-binding)

Predicted Domain #3
Region A:
Residues: [394-508]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKSADDFIDK HIAELIFYME ELRAHVRKYG PVMQRYYVQY LSGFDAVVLN ELVQNLSVCP  60
   61 EDESIIMSSF VNTMTSLSVK QVEDGEVFDF RGMRLDWFRL QAYTSVSKAS LGLAD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.979 a.24.17 Group V grass pollen allergen
View Download 0.976 a.24.17 Group V grass pollen allergen
View Download 0.954 a.29.16 Description not found.
View Download 0.927 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.920 a.24.3 Cytochromes
View Download 0.910 a.24.18 Description not found.
View Download 0.900 a.24.3 Cytochromes
View Download 0.786 a.24.3 Cytochromes
View Download 0.773 a.24.13 Domain of the SRP/SRP receptor G-proteins

Predicted Domain #4
Region A:
Residues: [509-653]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HRELGKMMNT IIFHTKMVDS LVEMLVETSD LSIFCFYSRA FEKMFQQCLE LPSQSRYSIA  60
   61 FPLLCTHFMS CTHELCPEER HHIGDRSLSL CNMFLDEMAK QARNLITDIC TEQCTLSDQL 120
  121 LPKHCAKTIS QAVNKKSKKQ TGKKG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.869 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.862 a.215.1 Description not found.
View Download 0.786 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.783 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.767 a.29.8 Description not found.
View Download 0.741 a.25.1 Ferritin-like
View Download 0.690 a.133.1 Phospholipase A2, PLA2
View Download 0.652 a.74.1 Cyclin-like
View Download 0.571 a.118.8 TPR-like
View Download 0.505 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.392 a.126.1 Serum albumin-like
View Download 0.349 a.16.1 S15/NS1 RNA-binding domain
View Download 0.345 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.321 d.110.4 SNARE-like

Predicted Domain #5
Region A:
Residues: [654-817]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPEREKPGVE SMRKNRLVVT NLDKLHTALS ELCFSINYVP NMVVWEHTFT PREYLTSHLE  60
   61 IRFTKSIVGM TMYNQATQEI AKPSELLTSV RAYMTVLQSI ENYVQIDITR VFNNVLLQQT 120
  121 QHLDSHGEPT ITSLYTNWYL ETLLRQVSNG HIAYFPAMKA FVNL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [818-933]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTENELTFNA EEYSDISEMR SLSELLGPYG MKFLSESLMW HISSQVAELK KLVVENVDVL  60
   61 TQMRTSFDKP DQMAALFKRL SSVDSVLKRM TIIGVILSFR SLAQEALRDV LSYHIP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.977 a.47.1 STAT
View Download 0.949 a.2.14 Description not found.
View Download 0.946 a.47.1 STAT
View Download 0.938 a.2.7 tRNA-binding arm
View Download 0.935 a.2.7 tRNA-binding arm
View Download 0.924 a.2.7 tRNA-binding arm
View Download 0.920 a.2.7 tRNA-binding arm
View Download 0.878 a.47.2 t-snare proteins
View Download 0.855 d.67.3 Ribosome recycling factor, RRF
View Download 0.778 d.67.3 Ribosome recycling factor, RRF
View Download 0.761 d.67.3 Ribosome recycling factor, RRF
View Download 0.738 a.7.8 GAT domain
View Download 0.725 d.67.3 Ribosome recycling factor, RRF
View Download 0.725 d.67.3 Ribosome recycling factor, RRF

Predicted Domain #7
Region A:
Residues: [934-1128]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLVSSIEDFK DHIPRETDMK VAMNVYELSS AAGLPCEIDP ALVVALSSQK SENISPEEEY  60
   61 KIACLLMVFV AVSLPTLASN VMSQYSPAIE GHCNNIHCLA KAINQIAAAL FTIHKGSIED 120
  121 RLKEFLALAS SSLLKIGQET DKTTTRNRES VYLLLDMIVQ ESPFLTMDLL ESCFPYVLLR 180
  181 NAYHAVYKQS VTSSA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle