YRC Public Data Repository - Protein Structure Prediction

Protein:	TM9SF2
Organism:	Homo sapiens
Length:	663 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TM9SF2.

Description	E-value	Query Range	Subject Range
TM9S2_PONPY - Transmembrane 9 superfamily protein member 2 precursor - Pongo pygmaeus (Orangutan) TM9S2_PONAB - Transmembrane 9 superfamily member 2 OS=Pongo abelii GN=TM9SF2 PE=2 SV=1	0.0	[1..663]	[1..663]
gi\|73989439 - gi\|73989439\|ref\|XP_534172.2\| PREDICTED: similar to Transmembrane 9 superfamily protein member 2 prec...	0.0	[1..663]	[1..662]
TM9S2_RAT - Transmembrane 9 superfamily member 2 OS=Rattus norvegicus GN=Tm9sf2 PE=2 SV=1	0.0	[1..663]	[1..663]
TM9S2_MOUSE - Transmembrane 9 superfamily member 2 OS=Mus musculus GN=Tm9sf2 PE=1 SV=1	0.0	[1..663]	[1..662]
gi\|114650502 - gi\|114650502\|ref\|XP_001147355.1\| PREDICTED: transmembrane 9 superfamily member 2 isoform 1 [Pan trog...	0.0	[1..644]	[1..644]
gi\|50730617 - gi\|50730617\|ref\|XP_416972.1\| PREDICTED: hypothetical protein [Gallus gallus]	0.0	[35..663]	[23..651]
gi\|54648231, gi\|... - gi\|54648231\|gb\|AAH85025.1\| LOC495462 protein [Xenopus laevis], gi\|147898405\|ref\|NP_001088583.1\| hypo...	0.0	[14..663]	[6..651]
gi\|169153846, gi... - gi\|68354924\|ref\|XP_688457.1\| PREDICTED: similar to Transmembrane 9 superfamily member 2 [Danio rerio...	0.0	[15..663]	[8..658]

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Predicted Domain #1

Region A:
Residues: [1-90]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSARLPVLSP PRWPRLLLLS LLLLGAVPGP RRSGAFYLPG LAPVNFCDEE KKSDECKAEI  60
   61 ELFVNRLDSV ESVLPYEYTA FDFCQASEGK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [91-195]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPSENLGQVL FGERIEPSPY KFTFNKKETC KLVCTKTYHT EKAEDKQKLE FLKKSMLLNY  60
   61 QHHWIVDNMP VTWCYDVEDG QRFCNPGFPI GCYITDKGHA KDACV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [196-396]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISSDFHERDT FYIFNHVDIK IYYHVVETGS MGARLVAAKL EPKSFKHTHI DKPDCSGPPM  60
   61 DISNKASGEI KIAYTYSVSF EEDDKIRWAS RWDYILESMP HTHIQWFSIM NSLVIVLFLS 120
  121 GMVAMIMLRT LHKDIARYNQ MDSTEDAQEE FGWKLVHGDI FRPPRKGMLL SVFLGSGTQI 180
  181 LIMTFVTLFF ACLGFLSPAN R

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [397-530]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GALMTCAVVL WVLLGTPAGY VAARFYKSFG GEKWKTNVLL TSFLCPGIVF ADFFIMNLIL  60
   61 WGEGSSAAIP FGTLVAILAL WFCISVPLTF IGAYFGFKKN AIEHPVRTNQ IPRQIPEQSF 120
  121 YTKPLPGIIM GGIL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [531-663]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PFGCIFIQLF FILNSIWSHQ MYYMFGFLFL VFIILVITCS EATILLCYFH LCAEDYHWQW  60
   61 RSFLTSGFTA VYFLIYAVHY FFSKLQITGT ASTILYFGYT MIMVLIFFLF TGTIGFFACF 120
  121 WFVTKIYSVV KVD

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits