YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7445594, gi\|4...
Organism:	Homo sapiens
Length:	634 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7445594, gi|4....

Description	E-value	Query Range	Subject Range
gi\|56478652, gi\|... - gi\|56478652\|ref\|YP_160241.1\| ABC transporter, ATP-binding protein [Aromatoleum aromaticum EbN1], gi\|...	440.0	[0..84]	[634..39]
gi\|15158466, gi\|... - gi\|15890270\|ref\|NP_355942.1\| hypothetical protein AGR_L_318 [Agrobacterium tumefaciens str. C58], gi... gi\|25384809 - pir\|\|E98150 hypothetical ABC transporter ATP-binding protein in bcr 5'region [imported] - Agrobacter...	430.0	[0..80]	[634..40]
gi\|91688899, gi\|... - gi\|91784945\|ref\|YP_560151.1\| ABC oligopeptide/dipeptide transporter, duplicated ATPase subunits [Bur...	427.0	[0..66]	[634..1]
gi\|114616800 - gi\|114616800\|ref\|XP_001139777.1\| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]	424.0	[0..1]	[634..1]
gi\|48855897 - gi\|48855897\|ref\|ZP_00310055.1\| COG1123: ATPase components of various ABC-type transport systems, con... gi\|110636885, gi... - gi\|110636885\|ref\|YP_677092.1\| ABC transporter, ATP-binding protein [Cytophaga hutchinsonii ATCC 3340...	422.0	[0..85]	[615..13]
gi\|109626138, gi... - gi\|110668391\|ref\|YP_658202.1\| ABC-type dipeptide/oligopeptide/nickel transport systems, ATP-binding ...	422.0	[0..83]	[634..2]
gi\|69275750, gi\|... - gi\|69275750\|ref\|ZP_00611498.1\| Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-termin...	422.0	[0..69]	[634..3]
gi\|115258954, gi... - gi\|116254306\|ref\|YP_770144.1\| putative ATP-binding component of ABC transporter [Rhizobium leguminos...	421.0	[0..74]	[634..1]
gi\|62425223 - gi\|62425223\|ref\|ZP_00380359.1\| COG1123: ATPase components of various ABC-type transport systems, con...	421.0	[0..79]	[634..12]

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Predicted Domain #1

Region A:
Residues: [1-82]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSDLAKKKA AKKKEAAKAR QRPRKGHEEN GDVVTEPQVA EKNEANGRET TEVDLLTKEL  60
   61 EDFEMKKAAA RAVTGVLASH PN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [83-517]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STDVHIINLS LTFHGQELLS DTKLELNSGR RYGLIGLNGI GKSMLLSAIG KREVPIPEHI  60
   61 DIYHLTREMP PSDKTPLHCV MEVDTERAML EKEAERLAHE DAECEKLMEL YERLEELDAD 120
  121 KAEMRASRIL HGLGFTPAMQ RKKLKDFSGG WRMRVALARA LFIRPFMLLL DEPTNHLDLD 180
  181 ACVWLEEELK TFKRILVLVS HSQDFLNGVC TNIIHMHNKK LKYYTGNYDQ YVKTRLELEE 240
  241 NQMKRFHWEQ DQIAHMKNYI ARFGHGSAKL ARQAQSKEKT LQKMMASGLT ERVVSDKTLS 300
  301 FYFPPCGKIP PPVIMVQNVS FKYTKDGPCI YNNLEFGIDL DTRVALVGPN GAGKSTLLKL 360
  361 LTGELLPTDG MIRKHSHVKI GRYHQHLQEQ LDLDLSPLEY MMKCYPEIKE KEEMRKIIGR 420
  421 YGLTGKQQVS PIRNL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.522879
Match:	2iw3A
Description:	No description for 2iw3A was found.

Predicted Domain #3

Region A:
Residues: [518-634]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDGQKCRVCL AWLAWQNPHM LFLDEPTNHL DIETIDALAD AINEFEGGMM LVSHDFRLIQ  60
   61 QVAQEIWVCE KQTITKWPGD ILAYKEHLKS KLVDEEPQLT KRTHNVCTLT LASLPRP

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.4
Match:	1yqtA
Description:	RNase-L Inhibitor
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits