YRC Public Data Repository - Protein Structure Prediction

Protein:	ERGIC3
Organism:	Homo sapiens
Length:	383 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERGIC3.

Description	E-value	Query Range	Subject Range
ERGI3_DANRE - Endoplasmic reticulum-Golgi intermediate compartment protein 3 OS=Danio rerio GN=ergic3 PE=2 SV=1	0.0	[1..383]	[1..383]
gi\|109092202 - gi\|109092202\|ref\|XP_001098982.1\| PREDICTED: serologically defined breast cancer antigen 84 isoform 3...	0.0	[1..383]	[1..383]
ERGI3_XENTR - Endoplasmic reticulum-Golgi intermediate compartment protein 3 OS=Xenopus tropicalis GN=ergic3 PE=2 ...	0.0	[1..383]	[1..384]
ERGI3_PONPY - Endoplasmic reticulum-Golgi intermediate compartment protein 3 - Pongo pygmaeus (Orangutan) ERGI3_PONAB - Endoplasmic reticulum-Golgi intermediate compartment protein 3 OS=Pongo abelii GN=ERGIC3 PE=2 SV=1	0.0	[1..383]	[1..383]
gi\|62646208, gi\|... - gi\|62646208\|ref\|XP_215908.3\| PREDICTED: similar to serologically defined breast cancer antigen 84 is...	0.0	[1..383]	[56..443]
ERGI3_MOUSE - Endoplasmic reticulum-Golgi intermediate compartment protein 3 OS=Mus musculus GN=Ergic3 PE=1 SV=1	0.0	[1..383]	[1..383]
gi\|38327615, gi\|... - gi\|57208593\|emb\|CAI42842.1\| ERGIC and golgi 3 [Homo sapiens], gi\|38327615\|ref\|NP_938408.1\| serologic... CCDS13258.1_1 - null gi\|164623746 - gi\|164623746\|gb\|ABY64672.1\| ERGIC and golgi 3, isoform 1 (predicted) [Papio anubis]	0.0	[1..383]	[1..388]

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Predicted Domain #1

Region A:
Residues: [1-145]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEALGKLKQF DAYPKTLEDF RVKTCGGATV TIVSGLLMLL LFLSELQYYL TTEVHPELYV  60
   61 DKSRGDKLKI NIDVLFPHMP CAYLSIDAMD VAGEQQLDVE HNLFKQRLDK DGIPVSSEAE 120
  121 RHELGKVEVT VFDPDSLDPD RCESC

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [146-241]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGAEAEDIKC CNTCEDVREA YRRRGWAFKN PDTIEQCRRE GFSQKMQEQK NEGCQVYGFL  60
   61 EVNKVAGNFH FAPGKSFQQS HVHVHDLQSF GLDNIN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [242-383]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTHYIQHLSF GEDYPGIVNP LDHTNVTAPQ ASMMFQYFVK VVPTVYMKVD GEVLRTNQFS  60
   61 VTRHEKVANG LLGDQGLPGV FVLYELSPMM VKLTEKHRSF THFLTGVCAI IGGMFTVAGL 120
  121 IDSLIYHSAR AIQKKIDLGK TT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits