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View Structure Prediction Details

Protein: P4HB
Organism: Homo sapiens
Length: 508 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for P4HB.

Description E-value Query
Range
Subject
Range
PDIA1_RABIT - Protein disulfide-isomerase OS=Oryctolagus cuniculus GN=P4HB PE=2 SV=1
0.0 [1..508] [1..509]
PDIA1_PONAB - Protein disulfide-isomerase OS=Pongo abelii GN=P4HB PE=2 SV=1
PDIA1_PONPY - Protein disulfide-isomerase precursor - Pongo pygmaeus (Orangutan)
0.0 [1..508] [1..508]
gi|74212231 - gi|74212231|dbj|BAE40274.1| unnamed protein product [Mus musculus]
0.0 [15..508] [17..509]
gi|35655 - gi|35655|emb|CAA28775.1| unnamed protein product [Homo sapiens]
0.0 [1..508] [1..508]
gi|114670980 - gi|114670980|ref|XP_001164327.1| PREDICTED: prolyl 4-hydroxylase, beta subunit isoform 5 [Pan troglo...
0.0 [1..475] [1..475]
PDIA1_CRIGR - Protein disulfide-isomerase OS=Cricetulus griseus GN=P4HB PE=2 SV=1
4.0E-99 [1..508] [1..509]

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Predicted Domain #1
Region A:
Residues: [1-508]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRRALLCLA VAALVRADAP EEEDHVLVLR KSNFAEALAA HKYLLVEFYA PWCGHCKALA  60
   61 PEYAKAAGKL KAEGSEIRLA KVDATEESDL AQQYGVRGYP TIKFFRNGDT ASPKEYTAGR 120
  121 EADDIVNWLK KRTGPAATTL PDGAAAESLV ESSEVAVIGF FKDVESDSAK QFLQAAEAID 180
  181 DIPFGITSNS DVFSKYQLDK DGVVLFKKFD EGRNNFEGEV TKENLLDFIK HNQLPLVIEF 240
  241 TEQTAPKIFG GEIKTHILLF LPKSVSDYDG KLSNFKTAAE SFKGKILFIF IDSDHTDNQR 300
  301 ILEFFGLKKE ECPAVRLITL EEEMTKYKPE SEELTAERIT EFCHRFLEGK IKPHLMSQEL 360
  361 PEDWDKQPVK VLVGKNFEDV AFDEKKNVFV EFYAPWCGHC KQLAPIWDKL GETYKDHENI 420
  421 VIAKMDSTAN EVEAVKVHSF PTLKFFPASA DRTVIDYNGE RTLDGFKKFL ESGGQDGAGD 480
  481 DDDLEDLEEA EEPDMEEDDD QKAVKDEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.30103
Match: 2b5eA
Description: Crystal Structure of Yeast Protein Disulfide Isomerase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle