YRC Public Data Repository - Protein Structure Prediction

Protein:	KIF20A
Organism:	Homo sapiens
Length:	890 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KIF20A.

Description	E-value	Query Range	Subject Range
gi\|109078846 - gi\|109078846\|ref\|XP_001107307.1\| PREDICTED: similar to kinesin family member 20A [Macaca mulatta]	3.0E-89	[1..889]	[1..889]
gi\|114601917, gi... - gi\|55624822\|ref\|XP_517952.1\| PREDICTED: kinesin family member 20A isoform 3 [Pan troglodytes], gi\|11...	1.0E-88	[1..890]	[1..890]
KI20A_BOVIN - Kinesin-like protein KIF20A OS=Bos taurus GN=KIF20A PE=2 SV=1	6.0E-86	[1..890]	[1..888]
gi\|157170176 - gi\|157170176\|gb\|AAI52808.1\| Kinesin family member 1B [synthetic construct] gi\|123209319, gi... - gi\|86990460\|ref\|NP_997565.2\| kinesin family member 1B isoform b [Mus musculus], gi\|187465979\|emb\|CAQ...	3.0E-85	[147..825]	[5..673]
gi\|66347394, gi\|... - gi\|66347734\|emb\|CAI95220.1\| kinesin family member 1B [Homo sapiens], gi\|66347394\|emb\|CAI95752.1\| kin...	7.0E-85	[147..825]	[5..673]
gi\|52313412 - gi\|52313412\|dbj\|BAD51401.1\| kinesin-family protein KIF1Bbeta3 [Rattus norvegicus]	1.0E-84	[147..825]	[5..673]
gi\|50752112 - gi\|50752112\|ref\|XP_422658.1\| PREDICTED: similar to Kif1a protein [Gallus gallus]	7.0E-84	[193..826]	[161..800]

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Predicted Domain #1

Region A:
Residues: [1-131]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQGILSPPA GLLSDDDVVV SPMFESTAAD LGSVVRKNLL SDCSVVSTSL EDKQQVPSED  60
   61 SMEKVKVYLR VRPLLPSELE RQEDQGCVRI ENVETLVLQA PKDSFALKSN ERGIGQATHR 120
  121 FTFSQIFGPE V

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.69897
Match:	1gojA
Description:	Kinesin
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [132-500]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQASFFNLTV KEMVKDVLKG QNWLIYTYGV TNSGKTHTIQ GTIKDGGILP RSLALIFNSL  60
   61 QGQLHPTPDL KPLLSNEVIW LDSKQIRQEE MKKLSLLNGG LQEEELSTSL KRSVYIESRI 120
  121 GTSTSFDSGI AGLSSISQCT SSSQLDETSH RWAQPDTAPL PVPANIRFSI WISFFEIYNE 180
  181 LLYDLLEPPS QQRKRQTLRL CEDQNGNPYV KDLNWIHVQD AEEAWKLLKV GRKNQSFAST 240
  241 HLNQNSSRSH SIFSIRILHL QGEGDIVPKI SELSLCDLAG SERCKDQKSG ERLKEAGNIN 300
  301 TSLHTLGRCI AALRQNQQNR SKQNLVPFRD SKLTRVFQGF FTGRGRSCMI VNVNPCASTY 360
  361 DETLHVAKF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	69.0
Match:	1ia0K
Description:	Kif1a head-microtubule complex
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [501-890]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAIASQLVHA PPMQLGFPSL HSFIKEHSLQ VSPSLEKGAK ADTGLDDDIE NEADISMYGK  60
   61 EELLQVVEAM KTLLLKERQE KLQLEMHLRD EICNEMVEQM QQREQWCSEH LDTQKELLEE 120
  121 MYEEKLNILK ESLTSFYQEE IQERDEKIEE LEALLQEARQ QSVAHQQSGS ELALRRSQRL 180
  181 AASASTQQLQ EVKAKLQQCK AELNSTTEEL HKYQKMLEPP PSAKPFTIDV DKKLEEGQKN 240
  241 IRLLRTELQK LGESLQSAER ACCHSTGAGK LRQALTTCDD ILIKQDQTLA ELQNNMVLVK 300
  301 LDLRKKAACI AEQYHTVLKL QGQVSAKKRL GTNQENQQPN QQPPGKKPFL RNLLPRTPTC 360
  361 QSSTDCSPYA RILRSRRSPL LKSGPFGKKY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.39794
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits