| Protein: | DOK5 |
| Organism: | Homo sapiens |
| Length: | 306 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DOK5.
| Description | E-value | Query Range |
Subject Range |
|
|
9.0E-86 | [1..306] | [1..306] |
|
|
1.0E-85 | [1..306] | [1..306] |
|
|
2.0E-85 | [1..306] | [1..306] |
|
|
4.0E-84 | [1..306] | [1..307] |
|
|
2.0E-81 | [1..306] | [1..306] |
|
|
3.0E-81 | [1..306] | [1..327] |
|
|
3.0E-81 | [1..306] | [1..306] |
|
Region A: Residues: [1-132] |
1 11 21 31 41 51
| | | | | |
1 MASNFNDIVK QGYVRIRSRR LGIYQRCWLV FKKASSKGPK RLEKFSDERA AYFRCYHKVT 60
61 ELNNVKNVAR LPKSTKKHAI GIYFNDDTSK TFACESDLEA DEWCKVLQME CVGTRINDIS 120
121 LGEPDLLATG VE
|
| Detection Method: |  |
| Confidence: | 21.0 |
| Match: | 1wg7A |
| Description: | Solution structure of pleckstrin homology domain from human KIAA1058 protein |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.38944296108213 | bayes_pls_golite062009 |
| protein binding | 1.8661085728568 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase signaling protein activity | 0.577807513305932 | bayes_pls_golite062009 |
| receptor signaling protein activity | 0.25947065822274 | bayes_pls_golite062009 |
| insulin receptor binding | 0.242371008010579 | bayes_pls_golite062009 |
| receptor binding | 0.217665221914025 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.0628553386056759 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.0385577214695162 | bayes_pls_golite062009 |
|
Region A: Residues: [133-306] |
1 11 21 31 41 51
| | | | | |
1 REQSERFNVY LMPSPNLDVH GECALQITYE YICLWDVQNP RVKLISWPLS ALRRYGRDTT 60
61 WFTFEAGRMC ETGEGLFIFQ TRDGEAIYQK VHSAALAIAE QHERLLQSVK NSMLQMKMSE 120
121 RAASLSTMVP LPRSAYWQHI TRQHSTGQLY RLQDVSSPLK LHRTETFPAY RSEH
|
| Detection Method: | |
| Confidence: | 31.0 |
| Match: | 1j0wA |
| Description: | Crystal Structure Analysis of the Dok-5 PTB Domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.38944296108213 | bayes_pls_golite062009 |
| protein binding | 1.8661085728568 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase signaling protein activity | 0.577807513305932 | bayes_pls_golite062009 |
| receptor signaling protein activity | 0.25947065822274 | bayes_pls_golite062009 |
| insulin receptor binding | 0.242371008010579 | bayes_pls_golite062009 |
| receptor binding | 0.217665221914025 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.0628553386056759 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.0385577214695162 | bayes_pls_golite062009 |
