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View Structure Prediction Details

Protein: RPAP2
Organism: Homo sapiens
Length: 612 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPAP2.

Description E-value Query
Range
Subject
Range
RPAP2_RAT - RNA polymerase II subunit B1 CTD phosphatase Rpap2 OS=Rattus norvegicus GN=Rpap2 PE=1 SV=1
0.0 [1..609] [1..609]
gi|18257341, gi|... - gi|21450301|ref|NP_659160.1| RNA polymerase II associated protein 2 [Mus musculus], gi|18257341|gb|A...
0.0 [1..609] [1..614]
gi|13376202, gi|... - gi|13376202|ref|NP_079089.1| RNA polymerase II associated protein 2 [Homo sapiens], gi|10435038|dbj|...
0.0 [1..612] [1..612]
gi|114557714 - gi|114557714|ref|XP_001153375.1| PREDICTED: similar to Chromosome 1 open reading frame 82 isoform 2 ...
0.0 [1..612] [1..612]
gi|109010262 - gi|109010262|ref|XP_001099182.1| PREDICTED: similar to R08D7.2 [Macaca mulatta]
0.0 [1..612] [1..612]
RPAP2_PONAB - Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 OS=Pongo abelii GN=RPAP2 PE=2 SV=1
CA082_PONPY, RPA... - RNA polymerase II-associated protein 2 - Pongo pygmaeus (Orangutan), UPF0385 protein C1orf82 homolog...
0.0 [1..612] [1..612]

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Predicted Domain #1
Region A:
Residues: [1-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADFAGPSSA GRKAGAPRCS RKAAGTKQTS TLKQEDASKR KAELEAAVRK KIEFERKALH  60
   61 IVEQLLEENI TEEFLMECGR FITPAHYSDV VDERSIVKLC GYPLCQKKLG IVPKQKYKIS 120
  121 TKTNKVYDIT ERKSFCSNFC YQASKFFEAQ IPKTPVWVRE EERHPDFQLL KEEQSGHSGE 180
  181 EVQLCSKAIK TSDIDNPSHF EKQYESSSSS THSDSSSDNE QDFVSSIL

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 24.552842
Match: PF04181.4
Description: No description for PF04181.4 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [229-316]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGNRPNSTNI RPQLHQKSIM KKKAGHKANS KHKDKEQTVV DVTEQLGDCK LDSQEKDATC  60
   61 ELPLQKVNTQ SSSNSTLPER LKASENSE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [317-414]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEYSRSEITL VGISKKSAEH FKRKFAKSNQ VSRSVSSSVQ VCPEVGKRNL LKVLKETLIE  60
   61 WKTEETLRFL YGQNYASVCL KPEASLVKEE LDEDDIIS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [415-489]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPDSHFPAWR ESQNSLDESL PFRGSGTAIK PLPSYENLKK ETEKLNLRIR EFYRGRYVLG  60
   61 EETTKSQDSE EHDST

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [490-612]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPLIDSSSQN QIRKRIVLEK LSKVLPGLLV PLQITLGDIY TQLKNLVRTF RLTNRNIIHK  60
   61 PAEWTLIAMV LLSLLTPILG IQKHSQEGMV FTRFLDTLLE ELHLKNEDLE SLTIIFRTSC 120
  121 LPE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle