YRC Public Data Repository - Protein Structure Prediction

Protein:	GFAP
Organism:	Homo sapiens
Length:	432 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GFAP.

Description	E-value	Query Range	Subject Range
gi\|109481333 - gi\|109481333\|ref\|XP_001064779.1\| PREDICTED: similar to keratin Kb40 [Rattus norvegicus]	6.0E-64	[25..393]	[205..580]
gi\|109096771 - gi\|109096771\|ref\|XP_001093676.1\| PREDICTED: keratin, hair, basic, 4 [Macaca mulatta]	3.0E-63	[10..379]	[90..478]
gi\|73996557 - gi\|73996557\|ref\|XP_850166.1\| PREDICTED: similar to keratin, hair, basic, 3 [Canis familiaris]	3.0E-63	[10..379]	[139..515]
KRT84 - keratin 84	2.0E-62	[33..379]	[125..478]
gi\|114644580 - gi\|114644580\|ref\|XP_522389.2\| PREDICTED: keratin, hair, basic, 4 [Pan troglodytes]	1.0E-61	[33..379]	[125..478]

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Predicted Domain #1

Region A:
Residues: [1-306]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERRRITSAA RRSYVSSGEM MVGGLAPGRR LGPGTRLSLA RMPPPLPTRV DFSLAGALNA  60
   61 GFKETRASER AEMMELNDRF ASYIEKVRFL EQQNKALAAE LNQLRAKEPT KLADVYQAEL 120
  121 RELRLRLDQL TANSARLEVE RDNLAQDLAT VRQKLQDETN LRLEAENNLA AYRQEADEAT 180
  181 LARLDLERKI ESLEEEIRFL RKIHEEEVRE LQEQLARQQV HVELDVAKPD LTAALKEIRT 240
  241 QYEAMASSNM HEAEEWYRSK FADLTDAAAR NAELLRQAKH EANDYRRQLQ SLTCDLESLR 300
  301 GTNESL

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.88
Match:	2i1jA
Description:	No description for 2i1jA was found.

Predicted Domain #2

Region A:
Residues: [307-432]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERQMREQEER HVREAASYQE ALARLEEEGQ SLKDEMARHL QEYQDLLNVK LALDIEIATY  60
   61 RKLLEGEENR ITIPVQTFSN LQIRETSLDT KSVSEGHLKR NIVVKTVEMR DGEVIKESKQ 120
  121 EHKDVM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.69897
Match:	1gk4A
Description:	Vimentin coil
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits