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View Structure Prediction Details

Protein: PIGO
Organism: Homo sapiens
Length: 1089 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PIGO.

Description E-value Query
Range
Subject
Range
gi|114624319, gi... - gi|114624319|ref|XP_001165435.1| PREDICTED: phosphatidylinositol glycan anchor biosynthesis, class O...
0.0 [1..1089] [1..1089]
gi|109111122, gi... - gi|109111122|ref|XP_001091608.1| PREDICTED: similar to phosphatidylinositol glycan, class O isoform ...
0.0 [1..1089] [1..1089]
gi|21739535 - gi|21739535|emb|CAD38806.1| hypothetical protein [Homo sapiens]
0.0 [63..1089] [1..1026]
gi|109474835, gi... - gi|109476395|ref|XP_001069442.1| PREDICTED: similar to phosphatidylinositol glycan, class O [Rattus ...
0.0 [1..1089] [22..1121]
gi|60360026 - gi|60360026|dbj|BAD90232.1| mFLJ00350 protein [Mus musculus]
0.0 [1..1089] [20..1112]
gi|73971236 - gi|73971236|ref|XP_531985.2| PREDICTED: similar to phosphatidylinositol glycan, class O isoform 1 is...
0.0 [1..1089] [1..1087]

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Predicted Domain #1
Region A:
Residues: [1-446]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKASVLLFL AWVCFLFYAG IALFTSGFLL TRLELTNHSS CQEPPGPGSL PWGSQGKPGA  60
   61 CWMASRFSRV VLVLIDALRF DFAQPQHSHV PREPPVSLPF LGKLSSLQRI LEIQPHHARL 120
  121 YRSQVDPPTT TMQRLKALTT GSLPTFIDAG SNFASHAIVE DNLIKQLTSA GRRVVFMGDD 180
  181 TWKDLFPGAF SKAFFFPSFN VRDLDTVDNG ILEHLYPTMD SGEWDVLIAH FLGVDHCGHK 240
  241 HGPHHPEMAK KLSQMDQVIQ GLVERLENDT LLVVAGDHGM TTNGDHGGDS ELEVSAALFL 300
  301 YSPTAVFPST PPEEPEVIPQ VSLVPTLALL LGLPIPFGNI GEVMAELFSG GEDSQPHSSA 360
  361 LAQASALHLN AQQVSRFLHT YSAATQDLQA KELHQLQNLF SKASADYQWL LQSPKGAEAT 420
  421 LPTVIAELQQ FLRGARAMCI ESWARF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.0
Match: 1e1zP
Description: Arylsulfatase A
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [447-609]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLVRMAGGTA LLAASCFICL LASQWAISPG FPFCPLLLTP VAWGLVGAIA YAGLLGTIEL  60
   61 KLDLVLLGAV AAVSSFLPFL WKAWAGWGSK RPLATLFPIP GPVLLLLLFR LAVFFSDSFV 120
  121 VAEARATPFL LGSFILLLVV QLHWEGQLLP PKLLTMPRLG TSA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [610-813]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTNPPRHNGA YALRLGIGLL LCTRLAGLFH RCPEETPVCH SSPWLSPLAS MVGGRAKNLW  60
   61 YGACVAALVA LLAAVRLWLR RYGNLKSPEP PMLFVRWGLP LMALGTAAYW ALASGADEAP 120
  121 PRLRVLVSGA SMVLPRAVAG LAASGLALLL WKPVTVLVKA GAGAPRTRTV LTPFSGPPTS 180
  181 QADLDYVVPQ IYRHMQEEFR GRLE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [814-929]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTKSQGPLTV AAYQLGSVYS AAMVTALTLL AFPLLLLHAE RISLVFLLLF LQSFLLLHLL  60
   61 AAGIPVTTPG PFTVPWQAVS AWALMATQTF YSTGHQPVFP AIHWHAAFVG FPEGHG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [930-1089]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SCTWLPALLV GANTFASHLL FAVGCPLLLL WPFLCESQGL RKRQQPPGNE ADARVRPEEE  60
   61 EEPLMEMRLR DAPQHFYAAL LQLGLKYLFI LGIQILACAL AASILRRHLM VWKVFAPKFI 120
  121 FEAVGFIVSS VGLLLGIALV MRVDGAVSSW FRQLFLAQQR 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle